Steroids from the Leave of Persicaria perfoliata (L.) H. Gross

Authors

  • Md Sagar Hossain Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering University of Dhaka, Dhaka-1000, Bangladesh
  • NM Mofiz Uddin Khan Dhaka University of Engineering and Technology (DUET), Gazipur-1700, Bangladesh
  • Md Saiful Quddus Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka-1205, Bangladesh
  • AM Sarwaruddin Chowdhury Department of Applied Chemistry and Chemical Engineering, Faculty of Engineering University of Dhaka, Dhaka-1000, Bangladesh

DOI:

https://doi.org/10.3329/bpj.v22i2.42314

Keywords:

Persicaria perfoliata, Polygonaceae, -sitosterol, -sitosterol-D-glucoside, Brine shrimp lethality, antimicrobial screening.

Abstract

β-sitosterol (1) and β-sitosterol-D-glucoside (2) were isolated from the dichloromethane soluble fraction of a methanol extract of the leave of Persicaria perfoliata. The crude fraction was subjected to antimicrobial screening and brine shrimp lethality bioassay, where moderate antimicrobial activity was observed against most of the test organisms was seen. The hexane soluble fraction also displayed significant cytotoxic activity with LC50 0.64 μg/ml in brine shrimp lethality bioassay. This is the first report of occurrence of these compounds from this plant.

Bangladesh Pharmaceutical Journal 22(2): 224-227, 2019

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Published

2019-07-21

How to Cite

Hossain, M. S., Khan, N. M. U., Quddus, M. S., & Chowdhury, A. S. (2019). Steroids from the Leave of Persicaria perfoliata (L.) H. Gross. Bangladesh Pharmaceutical Journal, 22(2), 224–227. https://doi.org/10.3329/bpj.v22i2.42314

Issue

Vol. 22 No. 2 (2019)

Section

Articles