Exploring Pharmacological Potentials of p-Coumaric Acid: A Prospective Phytochemical for Drug Discovery

Authors

  • Anika Zaman Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Hasin Hasnat Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Zakaria Al Noman Fruits and Food Processing and Preservation Research Division, BCSIR Laboratories Rajshahi, Bangladesh Council of Scientific and Industrial Research, Rajshahi-6206, Bangladesh
  • Md Mirazul Islam Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Abdullah Al Nakib Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Swakshar Mukherjee Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Kabbo Saha Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Nazim Uddin Ahmed Drugs and Toxins Research Division, BCSIR Laboratories Rajshahi, Bangladesh Council of Scientific and Industrial Research, Rajshahi-6206, Bangladesh
  • Sania Ashrafi Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka Dhaka-1000, Bangladesh
  • Tanoy Saha Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Md Ashraful Islam Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh
  • Safaet Alam Drugs and Toxins Research Division, BCSIR Laboratories Rajshahi, Bangladesh Council of Scientific and Industrial Research, Rajshahi-6206, Bangladesh

DOI:

https://doi.org/10.3329/bpj.v26i2.67808

Keywords:

p-Coumaric acid, biosynthesis, antiproliferative, neuroprotective, nephroprotective, antioxidant, antimicrobial

Abstract

p-coumaric acid, commonly referred to as 4-hydroxycinnamic acid, is a phenolic acid, which has been subjected to much research in recognition of its beneficial properties against several diseases and its widespread distribution in the plant kingdom. This compound can be found in the free-state or coupled with other molecules in nature. It has demonstrated prospective pharmacological effects including antiproliferative, nephroprotective, neuroprotective, antioxidant and antimicrobial effects in addition to other biological properties through numerous in vivo, in vitro and clinical studies. This review reported a short summary on p-coumaric acid to provide fundamental information in its biosynthesis, plant sources, and pharmacological effects which may help in future research and development of novel therapeutics.

Bangladesh Pharmaceutical Journal 26(2): 185-194, 2023 (July)

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Author Biography

Kabbo Saha, Department of Pharmacy, State University of Bangladesh, Dhaka-1205, Bangladesh

 

 

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Published

2023-08-08

How to Cite

Zaman, A. ., Hasnat, H. ., Noman, Z. A. ., Islam, M. M. ., Nakib, A. A. ., Mukherjee, S. ., Saha, K., Ahmed, N. U. ., Ashrafi, S. ., Saha, T. ., Islam, M. A. ., & Alam, S. . (2023). Exploring Pharmacological Potentials of p-Coumaric Acid: A Prospective Phytochemical for Drug Discovery. Bangladesh Pharmaceutical Journal, 26(2), 185–194. https://doi.org/10.3329/bpj.v26i2.67808

Issue

Vol. 26 No. 2 (2023)

Section

Articles