Assessment of Phytochemical Constituents, Antimicrobial Activity, Impurity and Heavy Metal Content of Gynura nepalensis

Authors

  • Sayma Akter Nirzana Department of Pharmacy, East West University, Dhaka 1212, Bangladesh
  • Jannatun Noor Oishi School of Pharmacy, BRAC University, Dhaka, Bangladesh
  • Jakir Ahmed Chowdhury Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka
  • Tasnia Rahman Department of Pharmacy, University of Asia Pacific, Farmgate, Dhaka, Bangladesh
  • Tasnuva Sharmin Zaman Department of Pharmaceutical Sciences, North South University, Plot # 15, Block # B Bashundhara R/A, Dhaka 1229, Bangladesh
  • Rifat Ara Nisu Department of Pharmacy, Faculty of Science & Engineering, City University, Khagan, Birulia, Savar
  • Sabnam Roy Suma Department of Pharmacy, Faculty of Science & Engineering, City University, Khagan, Birulia, Savar
  • Abu Asad Chowdhury Molecular Pharmacology and herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • Shaila Kabir Molecular Pharmacology and herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh
  • Md Shah Amran Molecular Pharmacology and herbal Drug Research Laboratory, Department of Pharmaceutical Chemistry, University of Dhaka, Dhaka 1000, Bangladesh

DOI:

https://doi.org/10.3329/bpj.v27i2.75188

Keywords:

Gynura nepalensis, natural medicine, phytochemistry, heavy metal, antimicrobial activity, impurity.

Abstract

This study explores the multifaceted area of herbal medicine, focusing on Gynura nepalensis, a medicinal plant. The qualitative analyses confirmed the presence of alkaloids, glycosides, phenols, tannins, flavonoids, protein-amino acids, saponins, and carbohydrates. Terpenoids and resin were apparently missing. The antimicrobial activity of the plant extract was assessed and it revealed dose-dependent efficacy against microbial growth. Additionally, the study scrutinized the total ash content, suggesting a moderate level of impurity, and evaluated the heavy metal concentration, finding it well below acceptable limits. Overall, the findings establish the promising role of Gynura nepalensis in natural medicine, urging further investigations and potential applications in integrated healthcare.

Bangladesh Pharmaceutical Journal 27(2): 193-200, 2024 (July)     

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Published

2024-07-30

How to Cite

Nirzana, S. A., Oishi, J. N., Chowdhury, J. A., Rahman, T., Zaman, T. S., Nisu, R. A., Suma, S. R., Chowdhury, A. A., Kabir, S., & Amran, M. S. (2024). Assessment of Phytochemical Constituents, Antimicrobial Activity, Impurity and Heavy Metal Content of Gynura nepalensis. Bangladesh Pharmaceutical Journal, 27(2), 193–200. https://doi.org/10.3329/bpj.v27i2.75188

Issue

Vol. 27 No. 2 (2024)

Section

Articles