Assessment of Antibacterial, Antioxidant & Anti-inflammatory Activities and Phytochemical Screening of Typha elephantina Roxb. (Hogla) Leaves

Authors

  • Md Kawser Department of Pharmacy, Dhaka International University, Satarkul, Badda, Dhaka, Bangladesh
  • Sharmistha Dhar Shaily Department of Pharmacy, Dhaka International University, Satarkul, Badda, Dhaka, Bangladesh
  • Sumiya Akter Department of Pharmacy, State University of Bangladesh, South Purbachal, Bangladesh
  • Md Sabbir Hossain Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
  • Md Raihan Chowdhory Department of Pharmacy, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
  • Shahenul Islam Department of Pharmacy, Dhaka International University, Satarkul, Badda, Dhaka, Bangladesh
  • Md Raihan Sarkar Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh

DOI:

https://doi.org/10.3329/bpj.v28i1.79460

Keywords:

Typha elephantina, antibacterial, antioxidant, anti-inflammatory, phytochemical screening.

Abstract

Typha elephantina Roxb, locally known as ‘Hogla’ in Bangladesh, is widely found in wet areas. In this work, T. elephantina leaves were used for developing the methanolic crude extract, which afterwards went through antibacterial, antioxidant and anti-inflammatory assays in addition to phytochemical investigations. Alkaloids, carbohydrates, tannins, phenolics, carbohydrates and flavonoids were identified in the extract. The methanolic extract of the leaves of T. elephantina revealed the highest level of antibacterial activity against E. coli. It exhibited an IC50 of 42.02 μg/ml in the DPPH free radical scavenging assay. The total phenolic content (TPC) of it was 29.96 milligrams of gallic acid equivalents (GAE) per gram of test extract. In the anti-inflammatory assay, the extract reduced paw edema 28.8% (p < 0.05) and 38.83% (p < 0.01) in the third and fourth hours of carrageenan administration. Taken together, the leaves of T. elephantina might be considered biologically active.

Bangladesh Pharmaceutical Journal 28(1): 56-62, 2025 (January)

Downloads

Abstract
129
PDF
137

Downloads

Published

2025-01-30

How to Cite

Kawser, M., Shaily, S. D., Akter, S., Hossain, M. S., Chowdhory, M. R., Islam, S., & Sarkar, M. R. (2025). Assessment of Antibacterial, Antioxidant & Anti-inflammatory Activities and Phytochemical Screening of Typha elephantina Roxb. (Hogla) Leaves. Bangladesh Pharmaceutical Journal, 28(1), 56–62. https://doi.org/10.3329/bpj.v28i1.79460

Issue

Section

Articles