Screening of Anti-inflammatory and Analgesic Activities of Caulerpa Racemosa from the Bay of Bengal, Bangladesh

Authors

  • Khadiza Rezwana Chowdhury Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh
  • Md Abdul Alim Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh
  • Nazia Rifat Zaman Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh
  • Abu Nayem Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh
  • Ethneen Mustafa Audri Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh
  • Pujan Mondal Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh
  • Mohammad Nazir Hossain Department of Genetic Engineering and Biotechnology, Bangabandhu Sheikh Mujibur Rahman Maritime University, Dhaka-1216, Bangladesh

DOI:

https://doi.org/10.3329/brc.v9i2.67090

Keywords:

Caulerpa racemose, Ethanolic extract, Anti-inflammatory activity, Analgesic activity, HPLC, Phytochemical.

Abstract

Caulerpa spp; is a remarkably potential seaweed due to its pharmacological importance, high nutritional compositions, biological activities , and human health benefit. It is a species of ulvophyte green algae inhabiting mostly in the intertidal and shallow sub-tidal coastal regions in the Asia- Pacific and commonly consumed in South-East Asia for its high contents of vitamins and minerals. Besides its culinary uses, it is well-reported for its antibacterial, antifungal, diabetes, blood pressure, and lipid-lowering properties. However, to date, no extensive assessment of the diversity, distribution, and biological activity assay of these seaweeds found on the Bangladesh coast has been carried out. This study aimed at anti-inflammatory and analgesic studies of 50% ethanolic extract of Caulerpa racemosa. collected from St. Martin's Island, Bangladesh. Consequently, secondary metabolites such as steroids, flavonoids, glycoside, and saponin were also detected in the phytochemical assay. In the present study, 25 & 50mg/kg body weight of ethanolic extract of C. racemosa was used in hot plate, acetic acid, formic acid, and carrageenan-induced paw edema in Swiss albino mice showing C. racemosa extract has significant analgesic and anti-inflammatory properties.

Bioresearch Commu. 9(2): 1330-1339, 2023 (July)

Abstract
70
PDF
46

Downloads

Published

2023-06-20

How to Cite

Chowdhury, K. R. ., Alim, M. A. ., Zaman, N. R. ., Nayem, A., Audri, E. M. ., Mondal, P., & Hossain, M. N. . (2023). Screening of Anti-inflammatory and Analgesic Activities of Caulerpa Racemosa from the Bay of Bengal, Bangladesh. Bioresearch Communications, 9(2), 1330–1339. https://doi.org/10.3329/brc.v9i2.67090

Issue

Section

Original Article