Comparison Between Pethidine and Nalbuphine Hydrochloride Combating Epigastric Pain During Mopping of Intraperitoneal Blood in Lower Uterine Caesarean Section Operation

Authors

  • Md Ashraful Islam Assistant Professor, Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College, Dhaka-1000, Bangladesh
  • Shamima Akter Assistant Professor, Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College, Dhaka-1000, Bangladesh
  • Muhammad Khairul Bashar Assistant Professor, Department of Anaesthesiology, Critical Care and Pain Medicine, Sylhet MAG Osmani Medical College, Sylhet-3100, Bangladesh
  • Md Abdullah Tareq Bhuiyan Assistant Professor, Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College, Dhaka-1000, Bangladesh
  • Evana Samad Anaesthesiologist, National Institute of Ophthalmology and Hospital, Dhaka-1207, Bangladesh
  • Md Abu Kawsar Anaesthesiologist, Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College Hospital, Dhaka-1000, Bangladesh
  • Md Shahadat Hossain Junior Consultant, Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College Hospital, Dhaka-1000, Bangladesh
  • Taneem Mohammad Assistant Professor, Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College, Dhaka-1000, Bangladesh
  • Shuchana Chakma Postgraduate student, Department of Anaesthesiology, Critical Care and Pain Medicine, Rajshahi Medical College Hospital, Rajshahi-6100, Bangladesh
  • Hasnat Jahan Khan Postgraduate student, Department of Anaesthesiology, Critical Care and Pain Medicine, Sir Salimullah Medical College & Mitford Hospital, Dhaka-1100, Bangladesh

DOI:

https://doi.org/10.3329/cbmj.v12i1.64362

Keywords:

Caesarean section, subarachnoid block, pethidine, nalbuphine hydrochloride, intra-peritoneal mopping, epigastric pain, visual analogue scale

Abstract

A randomized prospective single blind trial was conducted in the Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh, between July 2021 and February 2022, to compare the effects of intravenous pethidine and nalbuphine hydrochloride combating epigastric pain and discomfort during mopping of intraperitoneal blood in lower uterine caesarean section (LUCS) operation. A total of 120 women participated in the study. They were randomly divided into two groups: group A (n=60) received intravenous diluted (with normal saline) 20-25 mg of pethidine, while group B (n=60) received intravenous diluted 10-20 mg of nalbuphine hydrochloride. There were no differences observed in mean age, weight, height, and duration of operation between two groups (P>0.05). However, participants of group B reported less or no epigastric pain and discomfort during mopping of intraperitoneal blood than that of group A (P<0.05), i.e., episode and intensity of pain measured by using visual analogue scales indicated that nalbuphine hydrochloride has a longer duration of action than pethidine. Our study revealed that intravenous diluted nalbuphine hydrochloride works better than pethidine to minimize epigastric pain and discomfort during mopping of intraperitoneal blood in lower uterine caesarean section (LUCS) operation.  

CBMJ 2023 January: Vol. 12 No. 01 P: 81-86

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Published

2023-02-19

How to Cite

Islam, M. A. ., Akter, S. ., Bashar, M. K. ., Bhuiyan, M. A. T. ., Samad, E. ., Kawsar, M. A. ., Hossain, M. S. ., Mohammad, T. ., Chakma, S. ., & Khan, H. J. . (2023). Comparison Between Pethidine and Nalbuphine Hydrochloride Combating Epigastric Pain During Mopping of Intraperitoneal Blood in Lower Uterine Caesarean Section Operation. Community Based Medical Journal, 12(1), 81–86. https://doi.org/10.3329/cbmj.v12i1.64362

Issue

Vol. 12 No. 1 (2023)

Section

Original Articles

License

Copyright (c) 2023 Md Ashraful Islam, Shamima Akter, Muhammad Khairul Bashar, Md Abdullah Tareq Bhuiyan, Evana Samad, Md Abu Kawsar, Md Shahadat Hossain, Taneem Mohammad, Shuchana Chakma, Hasnat Jahan Khan

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