Antimicrobial Efficacy of Endomethasone and Sealapex Sealers against Specific Endodontic Pathogens

Authors

  • Rownakara Chowdhury Assistant Professor and Head Department of General and Dental Pharmacology Mandy Dental College, Dhaka
  • Md Shamsul Alam Dean, Faculty of Dentistry Chairman, Department of Conservative Dentistry and Endodontics Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Md Golam Rubby Assistant Professor and Head Department of Oral Anatomy and Physiology Mandy Dental College, Dhaka
  • Golam Rabbi Bangabandhu Sheikh Mujib Medical University, Dhaka
  • SM Salahuddin Al Azad Assistant Professor and Head Department of Science of Dental Materials Mandy Dental College, Dhaka
  • Mst Amina Khatun Bangabandhu Sheikh Mujib Medical University, Dhaka
  • Tania Islam Assistant Professor and Head Department of Public Health Mandy Dental College, Dhaka
  • Nihar Sultana Mohakhali, Dhaka

DOI:

https://doi.org/10.3329/cdcj.v10i2.16317

Keywords:

Antibacterial activity, root canal sealer, agar diffusion test, Endomethasone, Sealapex

Abstract

Background: Antimicrobial efficacy is one of the desired properties of root canal sealer to eliminate the residual microorganisms from complex root canal system unaffected by chemomechanical preparation and intracanal medication. The aim of the study is to compare the antimicrobial effects of two different sealers, i.e. zinc oxide based Endomethasone and calcium hydroxide based Sealapex against E. faecalis, S. aureus and C. albicans which are considered most resistant microorganisms in the oral cavity.

Methods: Agar diffusion method was used in this study. The sealers were prepared according to manufacturers instruction and placed in prepared wells 36 agar plates inoculated with E. faecalis, S. aureus and C. albicans. All plates were incubated for 5 days at 370C. The zone of inhibition of each sealer was measured after 24 hours, 48 hours and 5 days interval in order to evaluate the antimicrobial efficacy in different time duration. Statistical analysis was performed by ANOVA, independent sample t test and paired t test as applicable. P value <0.05 was considered as statistically significant.

Results: Endomethasone produced largest zone of inhibition at all-time interval than that of Sealapex against all tested microorganisms. However, the zone of inhibition of Endomethasone reduced significantly after 48 hours. The antimicrobial efficacy of Sealapex gradually increased at all times interval.

Conclusion: The antimicrobial efficacy of Endomethasone against E. faecalis, S. aureus and C. albicans is higher than that of Sealapex.

DOI: http://dx.doi.org/10.3329/cdcj.v10i2.16317

City Dent. Coll. J Volume-10, Number-2, July-2013

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Published

2013-09-05

How to Cite

Chowdhury, R., Alam, M. S., Rubby, M. G., Rabbi, G., Azad, S. S. A., Khatun, M. A., Islam, T., & Sultana, N. (2013). Antimicrobial Efficacy of Endomethasone and Sealapex Sealers against Specific Endodontic Pathogens. City Dental College Journal, 10(2), 27–30. https://doi.org/10.3329/cdcj.v10i2.16317

Issue

Vol. 10 No. 2 (2013)

Section

Original Articles