Subclinical hypothyroidism & infertility: a review

Authors

  • HS Ferdous Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM), Dhaka
  • Faria Afsana Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM), Dhaka
  • Nazmul Kabir Qureshi Department of Medicine & Endocrinology, United Hospital Limited, Dhaka
  • Rushda SB Rouf Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM), Dhaka
  • Irfan N Noor Shundorpur Durgapur Union subcenter, Kaligonj, Jhenaidah
  • AA Parvez Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM), Dhaka
  • AS Mir Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM), Dhaka

DOI:

https://doi.org/10.3329/imcj.v8i1.22984

Keywords:

Subclinical Hypothyroidism, Infertility, TSH, L-thyroxine

Abstract

Subclinical hypothyroidism (SCH) may be of greater clinical importance in women with unexplained infertility, especially when the luteal phase is inadequate, and such patients should be investigated for thyroid dysfunction in detail. To date, studies investigating the association between SCH and infertility are still based on the high serum thyroid stimulating hormone (TSH) levels while some older studies are based on the presence of an abnormal serum TSH after a thyrotropin releasing hormone (TRH) stimulation test. The recommendation in the current guidelines to treat subclinical hypothyroidism is based on minimal evidence and it is thought that with treatment the potential benefits outweigh the potential risks. Thyroxine-replacement therapy should be started in patients with SCH caused by conditions which are at high risk of progression to overt hypothyroidism.

Ibrahim Med. Coll. J. 2014; 8(1): 17-24

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Author Biography

HS Ferdous, Department of Endocrinology, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorder (BIRDEM), Dhaka



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Published

2015-04-15

How to Cite

Ferdous, H., Afsana, F., Qureshi, N. K., Rouf, R. S., Noor, I. N., Parvez, A., & Mir, A. (2015). Subclinical hypothyroidism & infertility: a review. Ibrahim Medical College Journal, 8(1), 17–24. https://doi.org/10.3329/imcj.v8i1.22984

Issue

Vol. 8 No. 1 (2014)

Section

Review Articles