Comparative efficacy of tulathromycin versus a combination of florfenicoloxytetracycline in the treatment of undifferentiated respiratory disease in large numbers of sheep
Keywords:
Draxxin, Iran, Nuflor, Ovine, Oxipra, PneumoniaAbstract
The objective of this study was to compare the
efficacy of tulathromycin (TUL) with a combination
of florfenicol (FFC) and long-acting oxytetracycline
(LAOTC) in the treatment of naturally occurring
undifferentiated respiratory diseases in large
numbers of sheep. In this study, seven natural
outbreaks of sheep pneumonia in Garmsar, Iran were
considered. From these outbreaks, 400 sheep
exhibiting the signs of respiratory diseases were
selected, and the sheep were randomly divided into
two equal groups. The first group was treated with a
single injection of TUL (dosed at 2.5 mg/kg body
weight), and the second group was treated with
concurrent injections of FFC (dosed at 40 mg/kg bwt)
and LAOTC (dosed at 20 mg/kg bwt). In the first
group, 186 (93%) sheep were found to be cured 5 days
after the injection, and 14 (7%) sheep needed further
treatment, of which 6 (3%) were cured, and 8 (4%)
died. In the second group, 172 (86%) sheep were cured
after the injections, but 28 (14%) sheep needed further
treatment, of which 10 (5%) were cured, and 18 (9%)
died. This study revealed that TUL was more
efficacious as compared to the combined treatment
using FFC and LAOTC. As the first report, this field
trial describes the successful treatment of
undifferentiated respiratory diseases in large
numbers of sheep. Thus, TUL can be used for the
treatment of undifferentiated respiratory diseases in
sheep.
http://dx.doi.org/10.5455/javar.2015.b86
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