Jicama (Pachyrhizus erosus) fiber prevents excessive blood glucose and body weight increase without affecting food intake in mice fed with high-sugar diet

Authors

  • Putra Santoso Biology Department, Faculty of Mathematics and Natural Sciences, Andalas University, Padang, Indonesia
  • Astri Amelia Biology Department, Faculty of Mathematics and Natural Sciences, Andalas University, Padang, Indonesia
  • Resti Rahayu Biology Department, Faculty of Mathematics and Natural Sciences, Andalas University, Padang, Indonesia

Keywords:

Adipose tissue; diabetes; edible fiber; glucose intolerance; obesity

Abstract

Objective: Jicama (Pachyrhizus erosus) fiber has been documented to exert an immunomodu­latory effect both in vitro and in vivo. However, its beneficial effect against metabolic syndrome remains unknown. This study aimed to reveal whether the jicama fiber (JF) could prevent the development of diabetes and obesity caused by a high-sugar diet (HSD).

Materials and Methods: The JF was isolated from its tuberous part and subsequently used as a supplemental diet for adult male Bagg and Albino (BALB)/c mice fed with a HSD. Four different diet paradigms including normal diet, HSD (30% sucrose), and HSD in combination with 10% and 25% of JF, respectively, were deployed continuously for 8 weeks. Furthermore, the blood glucose level, glucose tolerance, body weight, food and water consumption as well as epididymal white adipose tissue (WAT) and interscapular brown adipose tissue (BAT) mass were determined.

Results: Our results revealed that supplementation of 25% JF could significantly prevent the blood glucose increase, excessive body weight gain, and glucose intolerance in mice fed with HSD. Moreover, 10% and 25% JF blunted the HSD-induced WAT mass gain but failed to counteract the depletion of BAT mass. Furthermore, the fiber supplementation elicited a minimum effect on rhythm and total food and water intake.

Conclusion: The JF could effectively sustain blood glucose homeostasis as well as improve body weight and WAT mass profile against the development of diabetes and obesity caused by HSD.

J. Adv. Vet. Anim. Res., 6(2): 222-230, June 2019

Downloads

Download data is not yet available.
Abstract
23
PDF
28

Downloads

Published

2019-06-13

How to Cite

Santoso, P., Amelia, A., & Rahayu, R. (2019). Jicama (Pachyrhizus erosus) fiber prevents excessive blood glucose and body weight increase without affecting food intake in mice fed with high-sugar diet. Journal of Advanced Veterinary and Animal Research, 6(2), 222–230. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/41764

Issue

Vol. 6 No. 2 (2019)

Section

Original Articles

License

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).