Hypoglycemic and hypolipidemic effects of two mangrove plants in a streptozotocininduced animal model of diabetes

Authors

  • Isam ELDin Mohamed ELAmin Abu Zeid Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudia Arabia.
  • Obidallah Hamdan Ali Al Jaghthmi Department of Biological Sciences, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudia Arabia.

Keywords:

Diabetic rats; R. mucronata; glucose; A. marina; insulin; lipid profile

Abstract

Objective: This study aims at evaluating the anti-diabetic, hypolipidemic, and pancreatic histo­pathological changes of Rhizophora mucronata and Avicennia marina.  Materials and Methods: The experimental rats were divided into eight groups (n = 15 each). Streptozotocin was used to induce diabetes. Daily oral administration of an aqueous extract from the leaves of R. mucronata and A. marina at 400 mg/kg BW, and a mixture of the two extracts for 6 weeks was assessed. The measurements of serum glucose, insulin, and lipid profile were carried out. Pancreatic specimens were collected from all groups and processed for pathological studies.  Results: The study revealed that the plant extracts restored the levels of diabetic markers and lipid profiles of diabetic rats, with no significant changes in non-diabetic ones. The extract of R. mucronata exhibited more promising anti-diabetic and hypolipidemic effects than A. marina singly or combined.  Conclusion: Leaf extracts from R. mucronata, singly or combined, and A. marina, induced a potent anti-diabetic and hypolipidemic potential in diabetic rats.

J. Adv. Vet. Anim. Res., 7(3): 421-428, Sep 2020

http://doi.org/10.5455/javar.2020.g437

Downloads

Download data is not yet available.
Abstract
23
PDF
31

Downloads

Published

2020-08-03

How to Cite

ELAmin Abu Zeid, I. E. M., & Jaghthmi, O. H. A. A. (2020). Hypoglycemic and hypolipidemic effects of two mangrove plants in a streptozotocininduced animal model of diabetes. Journal of Advanced Veterinary and Animal Research, 7(3), 421–428. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/75595

Issue

Vol. 7 No. 3 (2020)

Section

Original Articles

License

Copyright (c) 2020 Isam ELDin Mohamed ELAmin Abu Zeid, Obidallah Hamdan Ali Al Jaghthmi

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).