Feline infectious peritonitis: A comprehensive evaluation of clinical manifestations, laboratory diagnosis, and therapeutic approaches

Authors

  • Wassamon Moyadee Graduate Program in Animal Health and Biomedical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand
  • Supita Sunpongsri Department of Companion Animal Clinical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand
  • Kiattawee Choowongkomon Department of Biochemistry, Faculty of Science, Kasetsart University, Bangkok, Thailand
  • Sittiruk Roytrakul Functional Proteomics Technology Laboratory, Functional Ingredients and Food Innovation Research Group, National Center for Genetic Engineering and Biotechnology, National Science and Technology for Development Agency, Pathum Thani, Thailand
  • Amonpun Rattanasrisomporn Interdisciplinary of Genetic Engineering and Bioinformatics, Graduate School, Kasetsart University, Bangkok, Thailand
  • Natthasit Tansakul Department of Pharmacology, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand
  • Jatuporn Rattanasrisomporn Graduate Program in Animal Health and Biomedical Sciences, Faculty of Veterinary Medicine, Kasetsart University, Bangkok, Thailand

Keywords:

Cats; coronavirus; effusion; feline infectious peritonitis; prednisolone

Abstract

Objective: This study aimed to investigate the clinical and laboratory characteristics of naturally occurring feline infectious peritonitis (FIP) and estimate the median survival time of FIP cats treated with prednisolone to guide further therapeutic planning. Materials and Methods: In this retrospective study, data from a total of 116 cats with effusion were fully recorded. Forty-five FIP-diagnosed cats were enrolled for analysis. Results: The study findings indicate that FIP was a disease affecting cats aged 1–2 years and was highly prevalent among male cats. Clinical manifestations of FIP affected the digestive (60%), hematological (53.3%), respiratory (33.3%), neurological (6.7%), and ocular (4.4%) systems. Blood profiles revealed mild anemia, lymphopenia, thrombocytopenia, hypoalbuminemia, hyperglobulinemia, and an albumin to globulin ratio of 0.4. Fluid analysis and cytology of FIP cats demonstrated a transparent yellow fluid with a protein content of 6 gm/dl and a total nucleated cell count of approximately 5,000–10,000 cells. During the observation period, FIP cats treated with prednisolone exhibited a median survival time of 31 days. Conclusion: Confirming FIP cases can be challenging; therefore, a tentative diagnosis of FIP must be made with care. This study provided practical diagnostic tools to diagnose FIP based on clinical signs and multiple abnormalities, which allowed for more efficient and rapid detection.

Adv. Vet. Anim. Res., 11(1): 19-26, March 2024

http://doi.org/10.5455/javar.2024.k742

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Published

2024-03-12

How to Cite

Moyadee, W., Sunpongsri, S., Choowongkomon, K., Roytrakul, S., Rattanasrisomporn, A., Tansakul, N., & Rattanasrisomporn, J. (2024). Feline infectious peritonitis: A comprehensive evaluation of clinical manifestations, laboratory diagnosis, and therapeutic approaches. Journal of Advanced Veterinary and Animal Research, 11(1), 19–26. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/75891

Issue

Vol. 11 No. 1 (2024)

Section

Original Articles

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Copyright (c) 2024 Wassamon Moyadee

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