Influence of ethanolic extract of avocado (Persea americana Mill.) seed flour on the estrous cycle, the serum concentrations of reproductive hormones, and the activities of oxidative stress markers in female cavies (Cavia porcellus L.)

Authors

  • Dongmo Nguedia Arius Baulland Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Vemo Bertin Narcisse Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Tchoffo Hervé Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Mohamadou Adamou Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Chongsi Margaret Mary Momo Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Djuissi Motchewo Nadège Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Mahamat Tahir Markhous Adam Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.
  • Ngoula Ferdinand Department of Animal Sciences, Faculty of Agronomy and Agricultural Sciences, University of Dschang, Dschang, Cameroon.

Keywords:

Estrous cycle; female cavy; oxidative stress; Persea americana seed; reproduction

Abstract

Objective: The purpose of this study was to determine the effects of the ethanolic extract of avo­cado seed flour on the estrous cycle characteristics, the concentrations of reproductive hormones [luteinizing hormone (LH) and estradiol], and the activities of some tissues (ovarian and uterine) that are markers of oxidative stress in female guinea pigs (Cavia porcellus).  Materials and Methods: Twenty-four female cavies with normal estrous cycles and equivalent body weights (464.25 and 71.88 gm) were randomly assigned to four groups, each with six females. The control group received 1 ml of distilled water orally, whereas the EE100, EE200, and EE400 groups received 100, 200, and 400 mg/kg bw of ethanolic extract of Persea americana seed, respectively. Following that, three consecutive estrous cycles were observed using vaginal smears. After the trial, the females were slaughtered, and blood and organs were gathered for study.  Results: The mean duration of the estrus phase is considerably (p < 0.05) longer in group EE100 animals than in control animals. LH concentrations were substantially (p < 0.05) higher in females in group EE200 than in controls. Total cholesterol levels typically dropped in females in the extract groups, but only significantly (p < 0.05) in those in group EE100 compared to the control group. Serum estradiol levels increased considerably (p < 0.05) in treated females compared to controls. Catalase activity rose considerably (p < 0.05) in the ovaries of group EE400 when compared to the control. Superoxide dismutase activity rose considerably (p < 0.05) in the uterus of female cavies given the extract compared to the control.  Conclusion: Avocado seed ethanolic extract prolongs the estrus phase, increases estradiol and LH levels, and protects the uterus from oxidative stress in female cavies.

J. Adv. Vet. Anim. Res., 8(3): 501-510, September 2021

http://doi.org/10.5455/javar.2021.h540

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Published

2021-09-20

How to Cite

Baulland, D. N. A., Narcisse, V. B., Hervé, T., Adamou, M., Momo, C. M. M., Nadège, D. M., Adam, M. T. M., & Ferdinand, N. (2021). Influence of ethanolic extract of avocado (Persea americana Mill.) seed flour on the estrous cycle, the serum concentrations of reproductive hormones, and the activities of oxidative stress markers in female cavies (Cavia porcellus L.). Journal of Advanced Veterinary and Animal Research, 8(3), 501–510. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/76950

Issue

Vol. 8 No. 3 (2021)

Section

Original Articles

License

Copyright (c) 2021 Dongmo Nguedia Arius Baulland, Vemo Bertin Narcisse, Tchoffo Hervé, Mohamadou Adamou, Chongsi Margaret Mary Momo, Djuissi Motchewo Nadège, Mahamat Tahir Markhous Adam, Ngoula Ferdinand

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