Evaluation of antibacterial efficacy of garlic (Allium sativum) and ginger (Zingiber officinale) crude extract against multidrug-resistant (MDR) poultry pathogen

Authors

  • Zakaria Al Noman Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. https://orcid.org/0000-0002-6966-1611
  • Tasnia Tabassum Anika Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
  • Sabbya Sachi Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. https://orcid.org/0000-0003-3348-3320
  • Jannatul Ferdous Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. https://orcid.org/0000-0001-8585-2859
  • Yousuf Ali Sarker Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh.
  • Md Abdus Sabur Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. https://orcid.org/0000-0003-2457-6162
  • Md Tanvir Rahman Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. https://orcid.org/0000-0001-5432-480X
  • Mahmudul Hasan Sikder Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh, Bangladesh. https://orcid.org/0000-0001-8792-9397

Keywords:

Multidrug-resistant pathogen; alternative antibiotic; TLCBioautography

Abstract

Objective: The study is aimed to understand the antibacterial sensitivity of native and Indian varieties of garlic (Allium sativum) and ginger (Zingiber officinale) crude extracts against multidrug-resistant (MDR) poultry pathogen (Escherichia coli and Salmonella sp.). Materials and Methods: Thin layer chromatography (TLC) is used to identify the target spices’ bioactive antibacterial compounds. MDR E. coli and Salmonella sp. were isolated from poultry. The TLC-Bioautography technique was applied to explore the antibacterial potentiality of garlic and ginger. Results: Inhibitory activities of garlic were Zone of inhibition (ZI) = 14.03 ± 0.15 mm and 19.70 ± 0.36 mm, Minimum inhibitory concentration (MIC): 0.625 and 0.325 mg/ml, and ginger were ZI = 14.63 ± 0.30 mm and 11.56 ± 0.51mm, MIC: 9.0 mg/ml against E. coli and Salmonella sp., respectively. Two bands of garlic (Rf value = 0.31 and 0.50) and one band of ginger (Rf value = 0.71) showed inhibitory potential in TLC-Bioautography against both MDR isolates. Conclusion: Garlic and ginger were effective against MDR E. coli and Salmonella sp. These spices could be a suitable alternative during the antibiotic void.

J. Adv. Vet. Anim. Res., 10(2): 151–156, June 2023

http://doi.org/10.5455/javar.2023.j664

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Published

2023-06-30

How to Cite

Noman, Z. A., Anika, T. T., Sachi, S., Ferdous, J., Sarker, Y. A., Sabur, M. A., … Sikder, M. H. (2023). Evaluation of antibacterial efficacy of garlic (Allium sativum) and ginger (Zingiber officinale) crude extract against multidrug-resistant (MDR) poultry pathogen. Journal of Advanced Veterinary and Animal Research, 10(2), 151–156. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/80382

Issue

Vol. 10 No. 2 (2023)

Section

Original Articles

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Copyright (c) 2023 Zakaria Al Noman, Tasnia Tabassum Anika, Sabbya Sachi, Jannatul Ferdous, Yousuf Ali Sarker, Md Abdus Sabur, Md Tanvir Rahman, Mahmudul Hasan Sikder

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