Effects of edible bird’s nest and EDTA on cadmium toxicity exposed rats’ embryo production, quality, and pre- and post-embryo transfer pregnancy rates

Authors

  • Anmar Jasim Mohammed Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, University Putra Malaysia, Seri Kembangan, Malaysia; College of Veterinary Medicine, University of Fallujah, Fallujah, 31002, Iraq. https://orcid.org/0009-0002-4448-0096
  • Nurhusien Yimer Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, University Putra Malaysia, Seri Kembangan, Malaysia; Department of Veterinary Sciences, School of Medicine, International Medical University, Kuala Lumpur, Malaysia; Division of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia. https://orcid.org/0000-0003-3766-8971
  • Faez Firdaus Abdullah Jesse Department of Veterinary Clinical Studies, Faculty of Veterinary Medicine, University Putra Malaysia, Seri Kembangan, Malaysia. https://orcid.org/0000-0001-8119-3331
  • Wan Nor Fitri Wan Jaafar Farm and Exotic Animal Medicine and Surgery, Faculty of Veterinary Medicine, University Putra Serdang, Seri Kembangan, Malaysia. https://orcid.org/0000-0002-6198-2656
  • Ainu Husna Livestock Science Division, Malaysian Agricultural Research Institute, Serdang, Selangor 43400, Malaysia. https://orcid.org/0000-0002-0217-5272

Keywords:

Embryo transfer; Edible bird’s nest; Cadmium toxicity; pregnancy; blastocyst

Abstract

Objectives: The current study aimed to investigate the prophylactic potential of EBN compared to EDTA in mitigating Cd's toxic effects on pregnancy rates and embryonic development in rats. Materials and Methods: Ninety-eight female rats (Sprague Dawley) were divided into donor and recipient groups, with donors further divided into seven subgroups, including negative control, Cd-exposed, EBN-treated, and EDTA-treated groups. Embryos from donors were transferred to recipient rats, with EBN and Cd administered for 4 weeks and EDTA given only in the last 5 days for the donor group. Results: Results showed significant differences in pregnancy rates and blastocyst quality. EBN at 120 mg/kg BW led to higher blastocyst production and better quality compared to Cd-exposed groups. The highest pregnancy rates in recipient groups correlated with the highest blastocyst scores from donors. Conclusion: EBN at 120 mg/kg demonstrated significant protection against Cd toxicity and its effect on pregnancy rates, embryo production, quality, and pre- and post-embryo transfer, surpassing the effects of both 90 mg/kg EBN and EDTA. This study provides empirical evidence in support of the conventional belief in the positive impact of EBN on female reproduction.

J. Adv. Vet. Anim. Res., 11(4): 944–953, December 2024

http://doi.org/10.5455/javar.2024.k844

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Published

2024-12-29

How to Cite

Mohammed, A. J., Yimer, N., Jesse, F. F. A., Jaafar, W. N. F. W., & Husna, A. (2024). Effects of edible bird’s nest and EDTA on cadmium toxicity exposed rats’ embryo production, quality, and pre- and post-embryo transfer pregnancy rates. Journal of Advanced Veterinary and Animal Research, 11(4), 944–953. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/81125

Issue

Vol. 11 No. 4 (2024)

Section

Original Articles

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Copyright (c) 2024 Anmar Jasim Mohammed, Nurhusien Yimer, Faez Firdaus Abdullah Jesse, Wan Nor Fitri Wan Jaafar, Ainu Husna

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