A retrospective study of zoonotic tuberculosis among livestock farmers of Lahore district using one health approach

Authors

  • Rubab Maqsood Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan; Institute of Continuing Education and Extension, University of Veterinary and Animal Sciences, Lahore, Pakistan. https://orcid.org/0009-0000-4180-3641
  • Abdul Rehman Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Farhat Nazir Awan Provincial Diagnostic Laboratory, Livestock and Dairy Development, Lahore, Pakistan.
  • Hamad Bin Rashid Department of Veterinary Surgery and Pet Sciences, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Shakera Sadiq Gill Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Chanda Jabeen Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Gulshan Umbreen Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Rafia Akram Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan.
  • Mamoona Chaudhry Department of Epidemiology and Public Health, University of Veterinary and Animal Sciences, Lahore, Pakistan. https://orcid.org/0000-0002-3151-3648

Keywords:

Zoonotic tuberculosis; bovine TB; risk factors; retrospective

Abstract

Objectives: Tuberculosis (TB) affects humans and animals regardless of species type, causing huge economic losses and deaths worldwide. However, the mechanisms and risk factors of zoonotic transmission are not well known in Pakistan. The current study aimed to identify the potential risk factors associated with TB in farmers and their animals, particularly exposure to infected animals in Lahore District, Pakistan. Materials and Methods: The study consisted of two components utilizing the concept of One Health. In the first component, a retrospective case-control study of human subjects (cases = 25, control = 25) was conducted from December 2021 to July 2022. In the second component, a cross-sectional analysis of the cattle owned by selected participants (TB cases and healthy controls) was completed in the Lahore district. A single intradermal tuberculin skin test was used to determine TB infection in cattle. Results: A total of 25 TB cases and 25 healthy controls were enrolled. Males in cases were found (OR = 0.01, 95% CI: 0.0002–0.29, p = 0.014) less likely to get TB, cases older than 35 years(OR = 1.13 (95% CI: 1.05–1.24, p = 0.004), unmarried cases (OR = 32.20, 95% CI: 2.92–819.03, p = 0.014), being a smoker (OR = 21.87, 95% CI: 2.80–395.82, p = 0.011), and keeping animals inside the home (OR = 9.92, 95% CI: 1.29–134.61, p = 0.047) were identified as significant predictors of TB in humans in the final multivariable logistic regression. Out of 175 tested animals, 3/65 animals belonging to the cases and 1/110 animals belonging to the controls were found positive. The animals belonging to the TB cases were (OR = 7.76, 95% CI; 0.79–76.02) more likely to have a positive Single Comparative Intradermal Tuberculin Test test. The prevalence of bTB in animals belonging to the cases was 4.6% (95% CI, 1.26–12.58) compared to 0.9% (95% CI, 0.04–4.67) in animals of the control group. Conclusion: This study identified potential risk factors that could contribute to the complex web of TB transmission between humans and animals. Our findings could provide data to inform policy-making and intervention strategies to reduce TB’s burden in both populations. Embracing a holistic One Health perspective is imperative to effectively combat this shared health threat.

J. Adv. Vet. Anim. Res., 11(4): 967–978, December 2024

http://doi.org/10.5455/javar.2024.k847

Downloads

Download data is not yet available.
Abstract
25

Published

2024-12-27

How to Cite

Maqsood, R., Rehman, A., Awan, F. N., Rashid, H. B., Gill, S. S., Jabeen, C., … Chaudhry, M. (2024). A retrospective study of zoonotic tuberculosis among livestock farmers of Lahore district using one health approach . Journal of Advanced Veterinary and Animal Research, 11(4), 967–978. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/81130

Issue

Vol. 11 No. 4 (2024)

Section

Original Articles

License

Copyright (c) 2024 Rubab Maqsood, Abdul Rehman, Farhat Nazir Awan, Hamad Bin Rashid, Shakera Sadiq Gill, Chanda Jabeen, Gulshan Umbreen, Rafia Akram, Mamoona Chaudhry

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

Authors who publish with this journal agree to the following terms:

Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).