Association study of the CSN2 gene with milk yield in the Sapera goat

Authors

  • Santiananda Arta Asmarasari Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-0783-8733
  • Galih Ari Wirawan Siregar Department of Animal Science, Faculty of Agriculture, Universitas Sumatera Utara, Medan, Indonesia. https://orcid.org/0000-0002-1760-1633
  • Ferdy Saputra Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-7949-9777
  • Lisa Praharani Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-8878-7260
  • Zultinur Muttaqin Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-7765-2221
  • Diana Andrianita Kusumaningrum Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0003-2509-8625
  • Nurul Azizah Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0003-0076-3596
  • Wisri Puastuti Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-9424-3710
  • Dwi Yulistiani Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-1411-6755
  • Supardi Rusdiana Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0009-0008-1582-640X
  • Anneke Anggraeni Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0009-0007-8279-8886
  • Suyatno Suyatno Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0001-6859-5934
  • Teguh Ari Prabowo Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-8815-5909
  • Nurul Pratiwi Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0001-5334-5772
  • Cecep Hidayat Research Center for Animal Husbandry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Cibinong Science Center, Bogor, Indonesia. https://orcid.org/0000-0002-8856-661X

Keywords:

Sapera goat; CSN2 gene; association study; additive effect; dominance effects

Abstract

Objective: This research was conducted to assess the influence of CSN2 exon 7 milk production and the additive and dominance effects. Materials and Methods: DNA was isolated from 64 goats that possessed the CSN2 gene and subjected to a polymerase chain reaction and genotyping by Sanger sequencing. Genotype effect can be assessed through analysis of variance and the generalized linear model, which can estimate additive and dominance effects. Results: Dairy traits are greatly influenced by the crucial role played by the CSN2 gene. The influence of SNP g.8946C > T on milk yield (MY) is statistically significant (p < 0.05). Nevertheless, the impact of SNP g.8956G > A on MY is not statistically significant. Furthermore, the MY of Sapera goats is affected by both Parity (p < 0.01) and days in milk (p < 0.01). Conclusion: The CC genotype demonstrates a higher MY without noticeable additive or dominance effects. Evaluating the SNP g.8946C > T necessitates many samples and phenotypes.

J. Adv. Vet. Anim. Res., 12(4): 1211–1216, December 2025

http://doi.org/10.5455/javar.2025.l981

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Published

2026-04-22

How to Cite

Asmarasari, S. A., Siregar, G. A. W., Saputra, F., Praharani, L., Muttaqin, Z., Kusumaningrum, D. A., … Hidayat, C. (2026). Association study of the CSN2 gene with milk yield in the Sapera goat. Journal of Advanced Veterinary and Animal Research, 12(4), 1211–1216. Retrieved from https://banglajol.info/index.php/JAVAR/article/view/88548

Issue

Vol. 12 No. 4 (2025)

Section

Original Articles

License

Copyright (c) 2025 Santiananda Arta Asmarasari, Galih Ari Wirawan Siregar, Ferdy Saputra, Lisa Praharani, Zultinur Muttaqin, Diana Andrianita Kusumaningrum, Nurul Azizah, Wisri Puastuti, Dwi Yulistiani, Supardi Rusdiana, Anneke Anggraeni, Suyatno Suyatno, Teguh Ari Prabowo, Nurul Pratiwi, Cecep Hidayat

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