Association study of the CSN2 gene with milk yield in the Sapera goat
Keywords:
Sapera goat; CSN2 gene; association study; additive effect; dominance effectsAbstract
Objective: This research was conducted to assess the influence of CSN2 exon 7 milk production and the additive and dominance effects. Materials and Methods: DNA was isolated from 64 goats that possessed the CSN2 gene and subjected to a polymerase chain reaction and genotyping by Sanger sequencing. Genotype effect can be assessed through analysis of variance and the generalized linear model, which can estimate additive and dominance effects. Results: Dairy traits are greatly influenced by the crucial role played by the CSN2 gene. The influence of SNP g.8946C > T on milk yield (MY) is statistically significant (p < 0.05). Nevertheless, the impact of SNP g.8956G > A on MY is not statistically significant. Furthermore, the MY of Sapera goats is affected by both Parity (p < 0.01) and days in milk (p < 0.01). Conclusion: The CC genotype demonstrates a higher MY without noticeable additive or dominance effects. Evaluating the SNP g.8946C > T necessitates many samples and phenotypes.
J. Adv. Vet. Anim. Res., 12(4): 1211–1216, December 2025
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Copyright (c) 2025 Santiananda Arta Asmarasari, Galih Ari Wirawan Siregar, Ferdy Saputra, Lisa Praharani, Zultinur Muttaqin, Diana Andrianita Kusumaningrum, Nurul Azizah, Wisri Puastuti, Dwi Yulistiani, Supardi Rusdiana, Anneke Anggraeni, Suyatno Suyatno, Teguh Ari Prabowo, Nurul Pratiwi, Cecep Hidayat
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