High Likelihood of Meningitis with Late Onset Septicemia in Newborn

Authors

  • M Shahidullah Chairman, Department of Neonatology &, Pro-VC, BSMMU
  • MA Mannan Associate Professor, Department of Neonatology, BSMMU
  • MS Alam Department of Neonatology, BSMMU, Dhaka
  • MZ Uddin Department of Neonatology, BSMMU, Dhaka
  • AC Dey Assistant Professor, Department of Neonatology, BSMMU
  • SK Dey Assistant Professor, Department of Neonatology, BSMMU

DOI:

https://doi.org/10.3329/jbcps.v30i1.11362

Keywords:

Likelihood, Meningitis

Abstract

Neonatal meningitis must be recognized and treated quickly  to prevent death or disability. Incidence of neonatal  meningitis with late onset sepsis is higher in developing  countries than those of resource-rich countries. In neonates  signs and symptoms of serious infections are often obscured  and clinical examination cannot distinguish among septic  babies with or without meningitis. Clinicians often differ  whether neonates undergo lumber puncture or not to  distinguish septic babies with or without meningitis.  Abnormal CSF findings are often used to detect neonatal  meningitis and determine the type and length of antibiotic  therapy with proven sepsis and meningitis cases. This study  was conducted to evaluate the bacterial meningitis among  the late onset sepsis in newborns and to identify the clinical  manifestations that can distinguish septicemia from  meningitis in neonates.  Total 1706 admitted patient in NICU of Bangabandhu  Sheikh Mujib Medical University from January 2007 to  December 2009 were evaluated retrospectively. Among the  133 (27.94%) cases of suspected late onset sepsis 47(35.33%)  were proven sepsis, 63(47.37%) were probable sepsis and  23(17.29%) cases were clinical sepsis based on clinical  features laboratory reports and blood cultures. Among the  proven sepsis 12(42.85%) cases were found to have definitive  bacterial meningitis and 16(57.15%) were probable bacterial  meningitis. Among the provable sepsis only 1(12.50%) cases  were found to have definite bacterial meningitis and 7  (87.50%) cases were probable bacterial meningitis. There  were no meningitis have found among the clinical sepsis.  Neonatal meningitis frequently occurred in late onset sepsis.  The most frequent presenting clinical features for meningitis  cases are more or less similar to those of septicemic cases.  The data of the study suggest that newborns with a positive  blood culture are significantly more likely to have meningitis  than those with a negative blood culture.

 

DOI: http://dx.doi.org/10.3329/jbcps.v30i1.11362

 

J Bangladesh Coll Phys Surg 2012; 30: 17-23

 

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Published

2012-07-22

How to Cite

Shahidullah, M., Mannan, M., Alam, M., Uddin, M., Dey, A., & Dey, S. (2012). High Likelihood of Meningitis with Late Onset Septicemia in Newborn. Journal of Bangladesh College of Physicians and Surgeons, 30(1), 17–23. https://doi.org/10.3329/jbcps.v30i1.11362

Issue

Vol. 30 No. 1 (2012)

Section

Original Articles

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