Clinico-Pathological Study on Haemophilia: An Analysis of 50 Cases

Authors

  • MM Uddin AFIP, Dhaka Cantonment, Dhaka
  • MJ Rahman Haematology Dept., BSMMU, Dhaka
  • MM Rahman OKP Mission, Kuwait
  • SA Sultana MBBS, Student, FCPS Part-II (Medicine)
  • MS Shah Haematology Dept., BSMMU, Dhaka

DOI:

https://doi.org/10.3329/jbcps.v24i2.148

Keywords:

haemophilia

Abstract

A prospective study was carried out on the patients presenting with history of recurrent joint swelling and wound bleeding in outpatient department of Haematology, Bangabandhu Sheikh Mujib Medical University (BSMMU) and Armed Forces Institute of Pathology (AFIP), Dhaka Cantonment from January 2000 to December 2000. Fifty patients were studied. The predominant age group affected were between six and 15 years (44%). Recurrent joint swelling was the predominant presenting symptom (100%) followed by wound bleeding (52%) and bleeding after tooth extraction (38%). Thirty (60%) patients had positive family history of bleeding. Coagulation screening tests showed that 40 (80%) patients had prolonged activated partial thromboplastin time (APTT). Amongst these 40 patients, 32 (80%) were diagnosed as haemophilia-A and eight (20%) as haemophilia-B. Eighteen (45%) patients had mild haemophilia, 17 (42.50%) moderate haemophilia and five (12.50%) patients had severe haemophilia. Spontaneous bleeding history was present in seven (17.50%) patients, and 16 (35.50%) patients with moderate haemophilia and 17 (47%) patients with mild haemophilia had bleeding following trauma or surgery. (J Bangladesh Coll Phys Surg 2006; 24: 50-53)

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Author Biographies

MM Uddin, AFIP, Dhaka Cantonment, Dhaka

Dr. (Maj) Mohammed Mosleh Uddin, MBBS, MCPS, DCP, FCPS, Graded Specialist in Pathology, AFIP, Dhaka Cantonment, Dhaka.

MJ Rahman, Haematology Dept., BSMMU, Dhaka

Prof. Md. Jalilur Rahman, MBBS, M, Phil, FCPS, FRCP (Edin), Chairman, Haematology Dept., BSMMU, Dhaka

MM Rahman, OKP Mission, Kuwait

Dr. Md. Mizanur Rahman, MBBS, DCP, MCPS, FCPS, Pathologist, OKP Mission, Kuwait.

SA Sultana, MBBS, Student, FCPS Part-II (Medicine)

Dr. Syeda Adib Sultana, MBBS, Student, FCPS Part-II (Medicine)

MS Shah, Haematology Dept., BSMMU, Dhaka

Dr. Md. Salahuddin Shah, MBBS, DCP, MCPS, FCPS, Assistant Professor, Haematology Dept., BSMMU, Dhaka.

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How to Cite

Uddin, M., Rahman, M., Rahman, M., Sultana, S., & Shah, M. (2007). Clinico-Pathological Study on Haemophilia: An Analysis of 50 Cases. Journal of Bangladesh College of Physicians and Surgeons, 24(2), 50–53. https://doi.org/10.3329/jbcps.v24i2.148

Issue

Vol. 24 No. 2 (2006)

Section

Original Articles

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