Management of Sepsis: Recent Advancement

Authors

  • Md Ismail Patwary Professor, Department of Medicine, Sylhet Women?s Medical College, Sylhet
  • Mohammad Zabed Jillul Bari Assistant Professor, Department of Medicine, Sylhet MAG Osmani Medical College, Sylhet
  • Ishrat Tahsin Isha Assistant Registrar, Department of Medicine, Sylhet Women?s Medical College, Sylhet

DOI:

https://doi.org/10.3329/jbcps.v34i4.32488

Keywords:

Sepsis, severe sepsis, Septic shock

Abstract

Sepsis is a systemic, deleterious host response to infection leading to acute organ dysfunction secondary to documented or suspected infection and septic shock i.e. sepsis plus hypotension not reversed with fluid resuscitation. Severe sepsis is a major healthcare problem with an extremely high mortality rate of 30-60% and it is one of the most common reasons for critically ill patients to be admitted to an intensive care unit (ICU). Excessive inflammation and coagulation and suppression of fibrinolysis are the hallmarks of Sepsis. Our medical concern is to manage sepsis and to prevent multi organ failure (MOF). Making an early, accurate diagnosis of septic shock is the key to increasing survival rates. With no specific, effective anti-sepsis therapies available, management focuses on haemodynamic stabilization and rapid resuscitation, early source control, adequate and appropriate antibiotics, organ support and modulation of the septic responses are the cornerstones of treatment.

J Bangladesh Coll Phys Surg 2016; 34(4): 206-212

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Author Biography

Md Ismail Patwary, Professor, Department of Medicine, Sylhet Women?s Medical College, Sylhet



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Published

2017-05-07

How to Cite

Patwary, M. I., Bari, M. Z. J., & Isha, I. T. (2017). Management of Sepsis: Recent Advancement. Journal of Bangladesh College of Physicians and Surgeons, 34(4), 206–212. https://doi.org/10.3329/jbcps.v34i4.32488

Issue

Section

Review Articles