Polycystic Ovary Syndrome and its Relationship with Infertility and its Management
DOI:
https://doi.org/10.3329/jbcps.v39i1.50458Keywords:
words: polycystic ovary syndrome (PCOS), infertility, anovulation, hyperandrogenism, hyperinsulinemia, lifestyle modificationAbstract
Polycystic ovary syndrome (PCOS) is the most common and treatable endocrine dysfunction in fertile women. The pathophysiology of PCOS involves primary defects in the hypothalamic–pituitary axis, insulin secretion and action, and ovarian function.Studies show 20-40 percent of female first-degree relatives of women with PCOS also have the syndrome.Genetic studies have identified a link between PCOS and disordered insulin metabolism and hyperinsulinemia.PCOS is characterized by hyperandrogenism, irregular ovulatory cycle and metabolic derangement, including glucose intolerance and hyperinsulinemia. Hyperandrogenism is a clinical hallmark of PCOS.In women with PCOS, Ovulation problems are usually the primary cause of infertility. PCOS is the most common cause of anovulatory infertility; ∼ 90–95% of women seeking treatment for infertility have PCOS. PCOS may cause higher risk for infertility, type 2 diabetes, high blood pressure, and endometrial cancer. The most common symptoms are irregular period, weight gain, acne, and excessive facial and body hair. PCOS has no cure but there are multiple treatments that can reduce symptoms. Life style modification includingdiet and exercise, have shown a positive influence on women with PCOS.
J Bangladesh Coll Phys Surg 2021; 39(1): 53-58
Downloads
66
88
Downloads
Published
How to Cite
Issue
Section
License
Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Bangladesh College of Physicians and Surgeons and may not be reproduced by any means in whole or in part without the written consent of the publisher.
No part of the materials published in this journal may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Reprints of any article in the Journal will be available from the publisher.
