Hyperpigmentation with Vitamin B12 Deficiency in an Adolescent Girl

Authors

  • Syeda Humaida Hasan Consultant, Department of Neonatology, Chittagong Medical College Hospital, Chittagong, Bangladesh
  • Rasheda Samad Professor, Dept. of Pediatrics, Chittagong Medical College, Chittagong, Bangladesh
  • Jagadish C Das Professor, Dept. of Neonatology, Chittagong Medical College, Chittagong, Bangladesh
  • Ferdous Ara Postgraduate student, Dept. of Pediatrics, Chittagong Medical College, Chittagong, Bangladesh
  • Mohammad Abu Faisal Assistant Professor, Dept. of Gastroenterology, Cox’s Bazar Medical College, Chittagong, Bangladesh

DOI:

https://doi.org/10.3329/jbcps.v39i1.50461

Keywords:

Hyperpigmentation, Vitamin B12 deficiency

Abstract

Hyperpigmentation as primary symptom is rare in vitamin B12 deficiency. This adolescent non vegetarian girl presented with hyperpigmentation, anaemia, glossitis and weight loss. She was worked up to find out the cause of anemia and hyperpigmentation. Addison disease was a strong provisional diagnosis. Her cortisol level was normal and megaloblastic anemia due to vitamin B12 deficiency was found. All of her symptoms were dramatically improved by injectable cobalamin. As vitamin B12 deficiency is a treatable condition so it should be ruled out in patient presenting with hyperpigmentation. Early replacement therapy also prevents multisystem involvement like bone marrow failure and demyelinating neurological disease.

J Bangladesh Coll Phys Surg 2021; 39(1): 62-67

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Published

2020-11-25

How to Cite

Hasan, S. H., Samad, R., Das, J. C., Ara, F., & Faisal, M. A. (2020). Hyperpigmentation with Vitamin B12 Deficiency in an Adolescent Girl. Journal of Bangladesh College of Physicians and Surgeons, 39(1), 62–67. https://doi.org/10.3329/jbcps.v39i1.50461

Issue

Section

Case Reports