A 35-year-old male with Waldenstrom Macroglobulinemia

Authors

  • Tamina Hossain Medical Officer, Upazila Health Complex, Kuliarchar, Kishoreganj, Bangladesh
  • Afrin Dewan Medical Officer, Office of Upazila Health and Family Planning Officer, Kurigram Sadar, Kurigram, Bangladesh
  • Atikur Rahman Assistant Registrar, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh
  • Nihar Ranjan Das Indoor Medical Officer, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh
  • M M Nasir Uddin Indoor Medical Officer, Shaheed Suhrawardy Medical College Hospital Dhaka, Bangladesh
  • Mir Mahfuzul Hoque Chowdhury Professor of Medicine, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh
  • Mohammad Rafiqul Islam Professor of Medicine, Shaheed Suhrawardy Medical College Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jbcps.v41i4.66914

Keywords:

Waldenstrom Macroglobulinemia

Abstract

Waldenstrom macroglobulinemia is one type of non- Hodgkin lymphoma that presents with a wide range of clinical features mainly due to secretion of the IgM paraprotein and infiltration of lymphoplasmacytic cells. Patients with Waldenstrom macroglobulinemia may experience fatigue, unexplained weight loss, enlarged lymph nodes, abdominal swelling, weakness, nose bleeding, blurring of vision etc. Waldenstrom macroglobulinemia is a disease of elderly individuals. The median age at diagnosis is 65 years, with a slight male predominance. We reported a case of a 35-yearold male who presented with fever, abdominal pain, loose motion and epistaxis. Examination revealed cervical and inguinal lymphadenopathy with hepatosplenomegaly. Investigation revealed diffuse lymphocyte infiltration on bone marrow study . Protein electrophoresis showed monoclonal gammopathy with high serum IgM level. On the basis of clinical features and investigation reports finally we diagnosed that, this was a rare case of Waldenstrom macroglobulinemia in a young patient. The patient was transfused 5 units of whole blood and was treated following standard treatment protocol with dexamethasone, Bortezomib and G-CSF. Unfortunately, patient died 3 weeks after initiation of treatment.

J Bangladesh Coll Phys Surg 2023; 41(4): 325-328

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Published

2023-10-26

How to Cite

Tamina Hossain, Dewan, A. ., Rahman, A. ., Das, N. R. ., Uddin, M. M. N., Hoque Chowdhury, M. M. ., & Islam, M. R. . (2023). A 35-year-old male with Waldenstrom Macroglobulinemia. Journal of Bangladesh College of Physicians and Surgeons, 41(4), 325–328. https://doi.org/10.3329/jbcps.v41i4.66914

Issue

Vol. 41 No. 4 (2023)

Section

Case Reports

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