Dengue Encephalitis with ‘Double Doughnut Sign’ – A Rare Case Report

Authors

  • Abu Shahin Mohammed Mahbubur Rahman Assistant Professor of Medicine, Rajshahi Medical College, Rajshahi, Bangladesh
  • Muzakkir Rahman Honorary Medical Officer, Department of Medicine, Rajshahi Medical College, Rajshahi, Bangladesh
  • T Bari Assistant Professor of Medicine, Rajshahi Medical College, Rajshahi, Bangladesh
  • SM Alom Associate Professor of Medicine, Rajshahi Medical College, Rajshahi, Bangladesh

DOI:

https://doi.org/10.3329/jbcps.v41i40.69730

Keywords:

Dengue encephalitis, Dengue fever, Double Doughnut sign

Abstract

Dengue fever is one of the most common arboviral infections, and it is the world’s fastest-spreading tropical illness. According to the World Health Organization, fifty million cases of clinical dengue infections occur each year, posing a significant public health hazard, primarily in Southeast Asia and the Western Pacific. The clinical spectrum of dengue fever ranges from asymptomatic infection to dengue shock syndrome. Although dengue virus is non-neurotropic virus, there is increasing evidence for dengue viral neurotropism suggesting there may be an element of direct viral encephalitis. Encephalopathy has been thought to result from the multisystem derangement that occurs in severe dengue, with liver failure, shock and coagulopathy causing a cerebral insult.  Dengue encephalitis is a rare disease. We report dengue encephalitis in a 55-year-old female, admitted in Rajshahi Medical College Hospital, Rajshahi, Bangladesh who presented with fever, vomiting, and altered level of consciousness. Her serum dengue NS1 was positive. MRI of brain showed hyperintensity in both basal ganglia & cerebellar region, which is identical to “Double Doughnut sign” found specifically in dengue encephalitis.

J Bangladesh Coll Phys Surg 2023; 41: 96-98

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Published

2023-11-28

How to Cite

Mahbubur Rahman, A. S. M., Rahman, M. ., Bari, T., & Alom, S. (2023). Dengue Encephalitis with ‘Double Doughnut Sign’ – A Rare Case Report. Journal of Bangladesh College of Physicians and Surgeons, 41(40), 96–98. https://doi.org/10.3329/jbcps.v41i40.69730

Issue

Vol. 41, Dengue Supplement, October 2023

Section

Case Reports

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