Evaluation, Exploration and Management Strategies of a First Reported Rarest Case of Para-Bombay Blood Phenotype with E-Beta Thalassaemia from Bangladesh

Authors

  • Tashmim Farhana Dipta Professor and Head, Transfusion Medicine and Clinical Haematology Department, BIRDEM General Hospital and Ibrahim Medical College, Dhaka, Bangladesh
  • Amin Lutful Kabir Associate Professor, Haematology Department, BSMMU, Dhaka, Bangladesh
  • Mohammed Abdul Quader Associate Professor, Transfusion Medicine Department, Popular Medical College, Dhaka, Bangladesh
  • Farida Parvin Assistant Professor, Transfusion Medicine and Clinical Haematology Department , BIRDEM General Hospital and Ibrahim Medical College, Dhaka, Bangladesh
  • Ayesha Khatun Professor and Chairperson, Transfusion Medicine Department, BSMMU, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jbcps.v42i1.70653

Keywords:

Anti-H, Bangladesh, Bombay blood type, E-Beta Thalassaemia, ‘O’ cell, Para-Bombay Phenotype, Rare blood group registry, Saliva inhibition Study, Secretor.

Abstract

Human H/h genetic polymorphism in ABO blood group system is rare and evidenced with Bombay and Para-Bombay blood group. This patient a 27-year-old-young man having ‘E-Beta thalassaemia’ incidentally has been identified as a case of ‘Para-Bombay phenotype’ after exploring with proper blood grouping, antibody detection and saliva inhibition study. Previously he was diagnosed as ‘O’ RhD positive and had two events of transfusion reaction during ‘O’ positive blood transfusion. In literature search and browsing there is dearth information on Para-Bombay Phenotype with E-Beta Thalassaemia. So far to our knowledge, this is the first reported case from Bangladesh of patient having ‘E-Beta Thalassaemia’ evidenced with rare ‘Para-Bombay blood Phenotype’. This study explores the laboratory work-out on Para-Bombay Phenotype and evaluates treatment strategies on this phenotype with concomitant E-Beta Thalassaemia.

J Bangladesh Coll Phys Surg 2024; 42: 97-104

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Published

2024-01-10

How to Cite

Dipta, T. F. ., Kabir, A. L. ., Quader, M. A., Parvin, F. ., & Khatun, A. . (2024). Evaluation, Exploration and Management Strategies of a First Reported Rarest Case of Para-Bombay Blood Phenotype with E-Beta Thalassaemia from Bangladesh. Journal of Bangladesh College of Physicians and Surgeons, 42(1), 97–104. https://doi.org/10.3329/jbcps.v42i1.70653

Issue

Vol. 42 No. 1 (2024)

Section

Case Reports

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