Red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) as predictors of outcome in acute pancreatitis

Authors

  • Dipanwita Saha Assistant Professor, Department of Paediatrics, Shaheed Suhrawardy Medical College, Dhaka, Bangladesh
  • Probir Kumar Sutradhar Assistant Professor, Department of Surgery, Cox’s Bazar Medical College Hospital, Chattogram, Bangladesh
  • Md Shafiul Alam Assistant Professor, Pediatric Gastroenterology and Nutrition, Shaheed Suhrawardy Medical College, Dhaka, Bangladesh
  • Fahmida Islam Associate Professor, Pediatric Gastroenterology and Nutrition, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh
  • Anita Saha Assistant Professor of Pediatrics, OSD, DGHS, Dhaka, Bangladesh
  • Kaniz Fatema Junior consultant, Pediatric Gastroenterology and Nutrition, Sir Salimullah Medical College & Mitford Hospital, Dhaka, Bangladesh
  • Md Shariful Hassan Medical Officer, Department of Paediatric Gastroenteroenterology and Nutrition, BSMMU, Dhaka, Bangladesh
  • ASM Bazlul Karim Ex Professor & Chairman, Department of Paediatric Gastroenterology and Nutrition, BSMMU, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jbcps.v42i3.74208

Keywords:

Acute pancreatitis, predictors, outcome, NLR, RDW

Abstract

BACKGROUND

Acute pancreatitis is a commonly encountered emergency in children. It has always been tough to predict accurately among the patients who will become systemically unwell. Simple prognostic markers, such as red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR), could identify such patients. This study was done to assess the usefulness of those markers.

METHODS

This cross-sectional study was conducted from July 2018 to June 2020 at department of Pediatric Gastroenterology and Nutrition, BSMMU, Dhaka. Thirty-one children with abdominal pain diagnosed as acute pancreatitis were included by purposive sampling in the study.

RESULTS

The mean age of the pediatric patients was 11.19 (±3.45) years. The mean red cell distribution width was 14.99 (±2.96) and mean neutrophil-to-lymphocyte ratio was 4.49 (±3.99). Total thirty patients (97%) were recovered and one patient (3%) died in hospital stay. Thirteen patients (41.9%) developed complications among which ascites was more common (12, 38.7%). NLR> 5 was observed in higher proportion in the study subjects with complications (46.2%) than without complications (16.7%) without any statistically significant difference. RDW ≥14 was found in 53.8% study subjects with complications and 50% without complications. However, no statistically significant difference was found. Length of hospital stay was longer in patients with NLR >5 than with NLR ≤5. RDW <14 was associated with longer hospital stay than RDW ≥14. There was no statistically significant difference. 

CONCLUSION

It was found that elevated RDW and NLR on admission had unfavorable clinical outcomes for pediatric patients with acute pancreatitis although statistical significance could not be established. Further multicenter studies with larger sample size are required for making some clinically applicable inference.

J Bangladesh Coll Phys Surg 2024; 42: 259-264

Downloads

Download data is not yet available.
Abstract
85
PDF
89

Downloads

Published

2024-07-28

How to Cite

Saha, D. ., Sutradhar, P. K. ., Alam, M. S. ., Islam, F. ., Saha, A. ., Fatema, K. ., Hassan, M. S. ., & Karim, A. B. . (2024). Red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) as predictors of outcome in acute pancreatitis. Journal of Bangladesh College of Physicians and Surgeons, 42(3), 259–264. https://doi.org/10.3329/jbcps.v42i3.74208

Issue

Vol. 42 No. 3 (2024)

Section

Original Articles

License

Submission of a manuscript for publication implies the transfer of the copyright from the author to the publisher upon acceptance. Accepted manuscripts become the permanent property of the Journal of Bangladesh College of Physicians and Surgeons and may not be reproduced by any means in whole or in part without the written consent of the publisher.

No part of the materials published in this journal may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Reprints of any article in the Journal will be available from the publisher.