Invasive Rhino-Orbital Mucormycosis in a Middle-Aged COVID-19 Patient: A Case Report

Authors

  • Forhad Uddin Hasan Chowdhury Registrar, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Animesh Kumar Kundu Resident, Department of Microbiology, Dhaka Medical College, Dhaka, Bangladesh
  • Sakib Aman Registrar, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Mohammad Shaharior Arafat Assistant Professor, Department of Head, Neck and Otolaryngology, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Md Shafiqul Bari Professor, Department of Medicine, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Md Titu Miah Professor, Department of Medicine and Principal, Dhaka Medical College, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jbcps.v43i4.84999

Keywords:

Rhino-orbital mucormycosis, COVID-19, Diabetes mellitus, Steroid therapy, Opportunistic fungal infection, Bangladesh

Abstract

Background: COVID-19 has been associated with diverse clinical manifestations, among which rhino-orbital-cerebral mucormycosis is increasingly reported. This severe, invasive fungal infection predominantly affects immunocompromised individuals. High-dose corticosteroid use during severe COVID-19, together with diabetes mellitus, increases susceptibility.

Case Presentation: We report one of the earliest cases of rhino-orbital-cerebral mucormycosis in Bangladesh occurring after severe COVID-19 pneumonia in a middle-aged diabetic male. The patient developed right-sided headache, facial pain, and acute vision loss while on corticosteroid therapy. Imaging and histopathology confirmed mucormycosis. Surgical debridement, exenteration of the affected eye, and antifungal therapy with amphotericin B followed by oral posaconazole led to clinical improvement.

Conclusion: This case underscores the importance of early suspicion of mucormycosis in diabetic COVID-19 patients treated with corticosteroids and demonstrates the critical value of multidisciplinary management in improving outcomes.

J Bangladesh Coll Phys Surg 2025; 43: 298-302

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Published

2025-10-30

How to Cite

Chowdhury, F. U. H., Kundu, A. K., Aman, S., Arafat, M. S., Bari, M. S., & Miah, M. T. (2025). Invasive Rhino-Orbital Mucormycosis in a Middle-Aged COVID-19 Patient: A Case Report. Journal of Bangladesh College of Physicians and Surgeons, 43(4), 298–302. https://doi.org/10.3329/jbcps.v43i4.84999

Issue

Vol. 43 No. 4 (2025)

Section

Case Reports

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