Adrenoleukodystrophy: An X-Linked Leukodystrophy With Predominent Neurological Manifestation : A Case Report

Authors

  • Shiuly Majumder Assistant Professor of Neurology, Chittagong Medical College, Chittagong, Bangladesh
  • Akramul Azam MD Student (Thesis Part) of Neurology Chittagong Medical College, Chittagong, Bangladesh
  • Rajat Kumar Biswas Senior Consultant of Obstetrics & Gynaecology, Chittagong General Hospital, Chittagong, Bangladesh
  • Pradip Kumar Kayasthagir Assistant Professor of Neurology, Chittagong Medical College, Chittagong, Bangladesh
  • Nandita Paul Senior Consultant of Medicine, 500 Beded Mugda Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jcmcta.v27i1.62305

Keywords:

Adrenoleukodystrophy; Cortical blindness; Bone marrow transplantation

Abstract

Leukodystrophy cases are not common in routine clinical practice. Among leukodystrophies adrenoleukodystrophy (ALD) cases are more common. It presents with neurologic and endocrine features with characteristic Megnetic Resonance Image (MRI) findings and biochemical changes. Early recognition of index case is important because dietary modification & supplementation with Lorenzo’s oil can slow progression of the disease course and can be life saving. Bone Marrow Transplantation (BMT) if performed in earlier stage of disease can be very rewarding to show stabilization and in some instances improvement of patient’s condition. More over prenatal diagnosis of affected boys can be performed by analyzing pedigree chart of an affected family members of this X-linked chromosomal disease.

JCMCTA 2016 ; 27 (1) : 68 - 71

Downloads

Download data is not yet available.
Abstract
23
PDF
34

Downloads

Published

2016-10-08

How to Cite

Majumder, S. ., Azam, A. ., Biswas, R. K. ., Kayasthagir, P. K. ., & Paul, N. . (2016). Adrenoleukodystrophy: An X-Linked Leukodystrophy With Predominent Neurological Manifestation : A Case Report. Journal of Chittagong Medical College Teachers' Association, 27(1), 68–71. https://doi.org/10.3329/jcmcta.v27i1.62305

Issue

Section

Case Reports