Correlation of HBeAg and Alanine Aminotransferase In Chronic Hbv Carriers

Authors

  • Shamima Akther Assistant Professor of Microbiology, Marine City Medical College, Chittagong, Bangladesh
  • Md Anwar Husain Professor of Microbiology (Retired), Chittagong Medical College, Chittagong, Bangladesh
  • HS Mubarak Hossain Junior Consultant of ENT, Upazila Health Complex, Boalkhali, Chittagong, Bangladesh
  • AHM Saiful Karim Chowdhury Lecturer of Microbiology, Chittagong Medical College, Chittagong, Bangladesh

DOI:

https://doi.org/10.3329/jcmcta.v27i2.62366

Keywords:

Chronic hepatitis; HBeAg; ALT

Abstract

Hepatitis B is a major public health problem worldwide, more than 350 million people have chronic infection in which may develop cirrhosis or cancer of the liver. The present study carried out among 61 previously diagnosed chronic hepatitis B patients. Among the 61 cases, 13(21.3%) were HBeAg positive and 48(78.7%) were HBeAg negative. In HBeAg positive cases, 53.85% had elevated and 46.15% had normal ALT levels. In contrast, majority (75%) of HBeAg negative patients had normal ALT levels. There was significance difference between HBeAg and ALT (p<0.05). In conclusion, the present study observed that there was positive correlation among HBeAg and ALT status in chronic HBV carriers. The combination of routine serology and biochemical test may be considered as an alternative to HBV DNA in evaluating the state of chronic HBV infection.

JCMCTA 2016 ; 27 (2) : 60 - 62

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Published

2017-02-25

How to Cite

Akther, S. ., Husain, M. A. ., Hossain, H. M. ., & Chowdhury, A. S. K. . (2017). Correlation of HBeAg and Alanine Aminotransferase In Chronic Hbv Carriers. Journal of Chittagong Medical College Teachers’ Association, 27(2), 60–62. https://doi.org/10.3329/jcmcta.v27i2.62366

Issue

Vol. 27 No. 2 (2016)

Section

Papers and Originals