Study on Correlation between Brandwein Points Based Histological Grading and Clinical Features of Mucoepidermoid Carcinoma of Salivary Glands

Authors

  • Mohammed Morshed Alam Assistant Professor of Oral and Maxillofacial Surgery, Dental Unit, Chittagong Medical College, Chattogram.
  • Niaz Ahmed Assistant Professor of Oral and Maxillofacial Surgery, Dental Unit, Chittagong Medical College, Chattogram.
  • Noushad Kaisar Pathan Assistant Professor of Oral and Maxillofacial Surgery, Dhaka Dental College, Dhaka.
  • Sumanta Kumar Gain Assistant Professor of Oral and Maxillofacial Surgery, Dhaka Dental College, Dhaka.
  • Shaheen Ahamed Assistant Professor of Oral and Maxillofacial Surgery, Dental Unit, Rajshahi Medical College, Rajshahi.
  • Mohammaed Kamal Uddin Assistant Professor of Dentistry, Dental Unit, Chittagong Medical College, Chattogram.
  • Sarah Fatima Sumaiya Lecturer of Oral Microbiology, Dental Unit, Chittagong Medical College, Chattogram.

DOI:

https://doi.org/10.3329/jcmcta.v33i2.66667

Keywords:

Brandwein point based histopatological grading system; Mucoepidermoid carcinoma; Salivary gland.

Abstract

Background: Mucoepidermoid Carcinoma (MEC) is the one malignancy in which histologic grading correlate with clinical behavior. The findings of the current study revealed that meticulous, uniform histopathologic grading is of importance of MEC of salivary glands. The aim of our study is to evaluate correlation between histopatholological grading with clinical features of mucoepidermoid carcinoma of salivary glands.

Materials and methods: This cross sectional study was conducted in patient attending tertiary level hospital in Dhaka, Bangladesh. A total 20 patients of histopathological grading of the mucoepidermoid carcinoma of salivary glands were undertaken using the currently established Brandwein point based histological grading systemand also evaluated the clinical features of the patients according to age sex and location. The data obtained were recorded and statistically analyzed.

Results: Twenty patients with mucoepidermoid carcinoma of salivary glands clinically and histopathologically evaluated. All tumors were graded histopathologically based on the criteria Brandweinpoint based histological grading system that among the 20 respondents 8 (40.0%) were diagnosed as MEC low grade, intermediate MEC 8 (40.0%), 4 (20.0%) were found as MEC high grade. Low grade tumors were not present any defining histolgical feature, intermedtate grade tumors revealed no bony invasion and necrosis but high grade tumors got all defining features.

Conclusion: Histological grading of MEC mucoepidermoid carcinoma of salivary glands which is apparently correlate with clinical findings found in our study.

JCMCTA 2022 ; 33 (2) : 66-71

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Published

2022-12-31

How to Cite

Alam, M. M. ., Ahmed, N. ., Pathan, N. K. ., Gain, S. K. ., Ahamed, S. ., Uddin, M. K. ., & Sumaiya, S. F. . (2022). Study on Correlation between Brandwein Points Based Histological Grading and Clinical Features of Mucoepidermoid Carcinoma of Salivary Glands. Journal of Chittagong Medical College Teachers' Association, 33(2), 66–71. https://doi.org/10.3329/jcmcta.v33i2.66667

Issue

Vol. 33 No. 2 (2022)

Section

Papers and Originals