Megnetic Ressonance Angiography Based Comparison of Age-Related Variations in Vascular Diameter of Circle of Willis in Bengali Population of Chattogram Division

Abstract

Background: Magnetic Resonance Angiography (MRA) is a non-invasive and non-radiation dependent most widely used method for detecting the morphology of Circle of Willis (COW). By using the 3D-TOF-MRA the present study was aimed to determine whether there is any differenceof COW vessels diameters between two specified age groups in Bengali population of Chattogram Division.

Materials and methods: This cross-sectional observational study was conducted in the department of Anatomy, Chittagong Medical College, Chattogram, upon 60 study subjects (29 were male and 31 were female) by dividing them into two groups (£40 years and >40 years of age). For statistical analysis unpaired student’s t-test was done and p-value was considered significant if it was <0.05 at 95% level of confidence.

Results: The participant's age range was between 02 -76 years with a mean ± SD age of 35.20±18.25 years.The mean vessel diameters of vessels were compared between two age groups (£40 years and >40 years of age) and majority of vessels showed statistically nonsignificant differences between two age groups except the diameter of Basilar Artery (BA) which shows significantly larger (p=0.027) in subjects >40 years of age.

Conclusion: Results of the present study provides some baseline data upon which further studies can be performed by other investigators in this field. These findings might also be helpful during the surgery at the skull base.

JCMCTA 2023 ; 34 (1) : 10-14