Current Diagnostic and Therapeutic Approach in the Management Of Thalassemia in Chattogram Region: A Hospital-Based Cross-Sectional Study

Abstract

Background: Thalassemias are the most common autosomal recessive hemolytic disorder.For survival, most patients require either blood transfusion or bone marrow transplantation and other supportive therapies.It is essential to carry out proper diagnostic and therapeutic approaches and regular follow up.This study aimed to evaluate the current diagnostic protocols and therapeutic approaches used for the management of thalassemia in Chattogram region.

Materials and methods: This cross-sectional study had been conducted with thalassemic patients in three tertiary care hospitals of Chattogram region, three district sadar hospitals and one voluntary thalassemia center of Fatikchari, Chattogram. A pre-structured questionnaire was used to record data,collected from a total of 307 patients (168 male and 139 female) from their prerecorded  hospital data and interviews of the patient and parents.

Results: Among 307 patients 279 patients had adequate informations and 270 patients had documented diagnosis. Findings revealed that HbE  b-thalassemia is the dominant type. We couldn’t detect any a-thalassemia patients in Chattogram region.

Conclusion: This study on thalassemia has provided valuable insights into the current diagnostic methods, treatment approaches, and associated factors regarding thalassemia.

JCMCTA 2026 ; 37 (1) : 11-16