Comparative Analysis of Liver Enzymes in Population With And Without Occupational Cement Dust Exposure

Abstract

Background: Prolong and repeated exposure to cement dust may cause serious occupational health hazards, affecting multiple organs including liver. Workers in cement factories are at high risk of such exposure. Chronic exposure to cement dust may impair liver function. This study is aimed to assess the effects of cement dust exposure on liver enzymes in cement factory workers.

Materials and methods: This cross sectionalstudy was conducted from July 2022-June 2023 in  Confidence Cement Factory Ltd. and in the Department of Physiology, Chittagong Medical College, Chattogram. Apparently healthy total 96 male subjects, aged between 20-50 years with BMI 18.5-27.5 kg/m 2  were includedby simple random sampling method according to inclusion and  exclusion criteria. A questionnaire along with general  information, about previous diseases, medical and family history were filled up by the researchers. Physiological parameters-pulse, systolic and diastolic blood pressurewere recorded. Serum Alanine Aminotransferase (ALT) Aspartate Aminotransferase (AST) and Alkaline Phosphatase (ALP) were measured.

Results: Result was compiled and compared after data collection by using SPSS-27. Chi-square and unpaired ‘t’test  were done as test of significance. p<0.05 was considered as statistically significant. Mean values of serum ALT and AST were significantly higher in cement dust exposed group.(p<0.05) Serum ALP showed nonsignificant changes between groups. (p>0.05)

Conclusion: Occupational exposure to cement dust is associated with alterations in liver function biomarkers, suggesting potential hepatocellular damage. Regular medical surveillance and preventive occupational health measures are recommended for at-risk populations.

JCMCTA 2026 ; 37 (1) : 55-60