A Case Report and Literature Review on Pregnancy with Acute Promyelocytic Leukemia with DIC

Authors

  • Tasneem Ara Associate Professor, Department of Hematology, Dhaka Medical College & Hospital, Dhaka
  • Mohiuddin Ahmed Khan Professor of Hematology, Department of Hematology, Dhaka Medical College & Hospital, Dhaka
  • Salma Afrose Professor of Hematology, Department of Hematology, Dhaka Medical College & Hospital, Dhaka.
  • Md Manirul Islam Assistant Professor, Department of Hematology, Dhaka Medical College & Hospital, Dhaka.
  • Mohammad Ali Medical Officer, Department of Hematology, Dhaka Medical College & Hospital, Dhaka
  • Humayra Nazneen Assistant Professor, Department of Hematology, Dhaka Medical College & Hospital, Dhaka.
  • Maftuha Akhter Assistant Professor, Department of Hematology, Dhaka Medical College & Hospital, Dhaka
  • Abu Yousuf Md Nazim Uddin Fellow Trainee, Department of Hematology, Dhaka Medical College & Hospital, Dhaka.

DOI:

https://doi.org/10.3329/jdmc.v23i2.25402

Keywords:

Acute promyelocytic leukemia, pregnancy, All trans-retinoic acid, Arsenic trioxide

Abstract

Acute promyelocytic leukemia (APL)-FAB-AML-M3 is now the most curable subtype of acute myeloblastic leukemia. The incidence of acute leukemia in pregnancy is rare. The occurrence of acute promyelocytic leukemia in pregnancy is also a very rare but management is very critical as APL is associated with life threatening hemorrhagic diathesis. Acute promyelocytic leukemia in pregnancy has not been reported in Bangladesh. Here we report a case of APL with DIC diagnosed during pregnancy. Clinical data and therapeutic approaches are presented. Her response to treatment was excellent resulted in a live birth and complete remission of her leukemia.

J Dhaka Medical College, Vol. 23, No.2, October, 2014, Page 262-265

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Author Biography

Tasneem Ara, Associate Professor, Department of Hematology, Dhaka Medical College & Hospital, Dhaka



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Published

2015-10-23

How to Cite

Ara, T., Khan, M. A., Afrose, S., Islam, M. M., Ali, M., Nazneen, H., Akhter, M., & Uddin, A. Y. M. N. (2015). A Case Report and Literature Review on Pregnancy with Acute Promyelocytic Leukemia with DIC. Journal of Dhaka Medical College, 23(2), 262–265. https://doi.org/10.3329/jdmc.v23i2.25402

Issue

Vol. 23 No. 2 (2014)

Section

Case Reports