Clinicopathological Profile of Cervical Cancer Patients Attending in a Specialized Hospital

Abstract

Background: Cervical cancer is one of the leading causes of death among women in our country. .It is a preventable disease and early carcinoma cervix can be cured by proper treatment. Lack of countrywide well accepted screening program of cervical cancer may be a cause of this hidden advancement of disease.

Objectives: To assess the clinical and pathological profile of patients with cervical cancer.

Method: This cross sectional descriptive study was conducted in the Department of Gynaeoncology of National Institute of Cancer Research & Hospital (NICRH) from January, 2011 to December, 2011. Initially 76 patients were enrolled in the study by purposive sampling. Thereafter they were scrutinized by eligibility criteria and ultimately 67 patients were finalized. A case record form was prepared which was pre-structured, interview and observation based and peer reviewed. Data regarding socio-demographic, clinical and pathological profiles were collected in standard data sheet. Data were recorded, compiled, edited and analyzed. P-value was determined as significant at <0.05.

Results: The mean age of 67 patients were 44.9±12.01 years (age range: 20-75 years). 74.6% patients were married, 79.1% were housewife and 50.7% were illiterate/only can sign. The household income was <10,000 BDT/month in case of 58.2% cases whereas 10,000-25,000 in 38.8% cases. Among study population 47.8% and 31.3%adenoc patients were staged as stage- II and stage-III, on the contrary 19.4% and 1.5% were staged as stage I and IV. Majority of patients 86.57% are suffering from aqueous cell carcinoma and only 13.43% had carcinoma. Most of the patient in advanced stage 32.75% in stage IIIB, 29.3% stage IIB. In this study all patients had excessive P/V discharge, among them 67.16% foul smelling and 19.4% blood stained, 764.1% irregular P/V bleeding and 86.56% postcoital bleeding. Regarding identifiable risk factors grand mutipara 79.1%,low socioeconomic group 58.2% and early marriage 49.25%

Conclusion: There are several risk factors available among our cervical cancer patients like early marriage, multipariy ,low socioeconomic coditioand, ,multiple sex partner. Most of them are suffering from squamous cell carcinoma. The alarming clinical presentation such as blood stained or foul smelling PV discharge, irregular PV bleeding and postcoital bleeding should be considered seriously for seeking medical attention.

J Dhaka Medical College, Vol. 26, No.2, October, 2017, Page 117-121