Post COVID Mucormycosis Prevention With Oro-Nasal Application of Povidone Iodine (Pvp-I)

Authors

  • Mostafa Kamal Arefin Registrar, Department of ENT and Head Neck Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Mala Khan Chief Scientific Officer & Director General (Adnl); Bangladesh Reference Institute of Chemical Measurements (BRICM), Dhaka, Bangladesh
  • SK Nurul Fattah Rumi Professor & Head, Dept. of ENT & Head Neck Surgery, Dhaka Medical College Hospital, Dhaka, Bangladesh
  • Md Nazmul Islam Director, Disease Control and Line Director, Directorate General of Health Services, Bangladesh
  • Debesh Chandra Talukder Associate Professor, Department of ENT and Head Neck Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh
  • Husne Qumer Osmani Associate Professor, Department of ENT and Head Neck Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh
  • Mohammod Delwar Hossain Classified ENT Specialist & Head Neck Surgeon, Combined Military Hospital, Chittagong Cantonment, Bangladesh
  • Muhammad Shaharior Arafat Assistant professor, Department of ENT and Head Neck Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh
  • Ahsanul Kaiser Nanotechnology and Theranostic, Bangladesh Council of Scientific and Industrial Research (BCSIR), Dhaka, Bangladesh
  • Md Sazzad Samad Indoor Medical Officer, Department of ENT and Head Neck Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh
  • Md Baha Uddin Consultant, ENT & Head Neck Cancer Hospital & Institute, Dhaka, Bangladesh
  • Joybaer Anam Chowdhury Internal medicine specialist, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh
  • As Saba Hossain Post Graduate Student, MPH Programme, AIUB , Bangladesh
  • Jahin Tareq Bhuiyan Residential Medical Officer, Department of ENT and Head Neck Surgery, Dhaka Medical College and Hospital, Dhaka, Bangladesh

DOI:

https://doi.org/10.3329/jdmc.v30i2.56923

Keywords:

Povidone Iodine, Mucormycosis, COVID-19

Abstract

In March 2020 WHO declared COVID-19 as pandemic while April 2021 Indian authority concede to declare a significantly increased incidence of “Black Fungus” among the COVID-19 patients. The primary route of infection for Mucormycosis or fungal infection following COVID-19 is inhalation or ingestion resulting accumulation of the agents in nose, para-nasal sinuses and mouth. The spores of black fungus intrude neural and vascular structure, which cause mucosal necrosis due to thrombosis in vasculature. The extension of the disease then increases through further destruction of bones of para-nasal sinus as well as neural and vascular route dissemination. We thought about removing, neutralizing or destroying the culprit fungi from its route of entry zone, i.e. nose and mouth. Povidone Iodine (PVP-I) is a microbicidal agent having effective fungicidal as well as virucidal and bactericidal property. PVP-I can be used in both oral and nasal cavity safely. Efficacy and safety of PVP-I is proved in nose in case of COVID-19. PVP-I is proved effective against different fungi at different concentration at different site. So, we recommend Povidone Iodine nasal spray or irrigation and mouthwash for gargling for these vulnerable group of patients in large scale to prevent post-COVID mucormycosis or fungal infection.

J Dhaka Med Coll. 2021; 30(2) : 176-179

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Published

2023-01-29

How to Cite

Arefin, M. K. ., Khan, M. ., Rumi, S. N. F. ., Islam, M. N. ., Talukder, D. C. ., Osmani, H. Q. ., Hossain, M. D. ., Arafat, M. S. ., Kaiser, A. ., Samad, M. S. ., Uddin, M. B. ., Chowdhury, J. A. ., Hossain, A. S. ., & Bhuiyan, J. T. . (2023). Post COVID Mucormycosis Prevention With Oro-Nasal Application of Povidone Iodine (Pvp-I). Journal of Dhaka Medical College, 30(2), 176–179. https://doi.org/10.3329/jdmc.v30i2.56923

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Original Articles