Study of Sensitivity Pattern of Metronidazole on Axenic Culture of <i>Entamoeba Histolytica</i> In Vitro

Authors

  • SK Sarker Assistant Professor, Department of Pharmacology & Therapeutics, Dhaka Medical College, Dhaka.
  • D Mondal Associate Scientist, Parasitology Laboratory, ICDDR,B, Dhaka.
  • MA Siddique Research Officer, Parasitology Laboratory, ICDDR,B, Dhaka.

DOI:

https://doi.org/10.3329/jdmc.v19i1.6256

Keywords:

Axenic culture, Entamoeba histolytica, Metronidazole

Abstract

Objective: To evaluate the sensitivity pattern of metronidazole against Entamoeba histolytica.

Design: It was an experimental study.

Settings: The study was carried out in Parasitology Laboratory, ICDDR,B Dhaka from January 2007 to June 2007.

Subjects: Entamoeba histolytica (Strain: MS 27 5030)

Main outcome measure: Minimum inhibitory concentration (MIC).

Results: In this study MIC of metronidazole was < 0.08 mg/ml.

Conclusion: The result suggests that metronidazole is still the standard drug for treatment of amoebiasis

Key words: Axenic culture; Entamoeba histolytica; Metronidazole.

DOI: 10.3329/jdmc.v19i1.6256

J Dhaka Med Coll. 2010; 19(1) : 65-66.

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How to Cite

Sarker, S., Mondal, D., & Siddique, M. (2010). Study of Sensitivity Pattern of Metronidazole on Axenic Culture of <i>Entamoeba Histolytica</i> In Vitro. Journal of Dhaka Medical College, 19(1), 65–66. https://doi.org/10.3329/jdmc.v19i1.6256

Issue

Vol. 19 No. 1 (2010)

Section

Review Articles