Role of Selected Antioxidants in Arsenic Toxicity: An Update

Authors

  • Abul Kalam Mohammad Yousuf Assistant Professor, Dept. of Pharmacology, Northern International Medical College (NIMC), Dhaka
  • Md Mazharul Islam Assistant Professor, Dept. of Forensic Medicine, NIMC, Dhaka
  • Ayasha Aktar Dept. of Physiology, Sir Salimullah Medical College, Dhaka
  • Md Rafiqul Bari Associate Professor, Dept. of Forensic Medicine, NIMC, Dhaka
  • A K M Shahidur Rahman Assistant Professor, Dept. of Pharmacology, Khwaja Yunus Ali Medical College, Shirajganj
  • Muhammad Mahbubul Alam Assistant Professor, Dept. of Pharmacology, East-West Medical College, Dhaka
  • Jannatul Ferdous Assistant Professor, Dept. of Biochemistry, NIMC, Dhaka
  • Md Anwar Hussain Professor and Head, Dept. of Forensic Medicine, NIMC, Dhaka
  • Shafique Md Jashim Uddin Professor and Head, Dept. of Forensic Medicine, Dhaka National Medical College (DNMC), Dhaka

DOI:

https://doi.org/10.3329/jdnmch.v19i1.77673

Keywords:

Arsenic, Free radicals, Reactive oxygen species (ROS), Oxidative stress, Antioxidants, Vitamin A, Vitamin C, Vitamin E, Zinc.

Abstract

Arsenic is an element in the environment causing oxidative damage in the exposed people leading to cell damage. Free radicals were generated during arsenic metabolism in cells. These free radicals are directly involved in oxidative damage in cells exposed to arsenic. Antioxidant levels are decreased in the body after arsenic exposure. Antioxidants can reduce or eliminate cellular damage caused by arsenic. This review article summarizes the role of some selected antioxidants in arsenic toxicity and also attempts to provide some update information regarding these selected antioxidants as better treatment regimen. We have selected vitamin A, C, E and zinc as antioxidants for this article keeping in view current concerns and literature available.

J. Dhaka National Med. Coll. Hos. 2013; 19 (01): 58-60

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Published

2013-03-30

How to Cite

Yousuf, A. K. M., Islam, M. M., Aktar, A., Bari, M. R., Rahman, A. K. M. S., Alam, M. M., Ferdous, J., Hussain, M. A., & Jashim Uddin, S. M. (2013). Role of Selected Antioxidants in Arsenic Toxicity: An Update. Journal of Dhaka National Medical College &Amp; Hospital, 19(1), 58–60. https://doi.org/10.3329/jdnmch.v19i1.77673

Issue

Vol. 19 No. 1 (2013)

Section

Review Articles