Chronic inflammatory demyelinating polyneuropathy maymimic with Motor neuron disease

Authors

  • Nurul Amin Khan Associate Professor, Department of Neuromedicine, Dhaka National Medical College
  • Shaheen Wadud Assistant Professor, Department of Neuromedicine, Dhaka National Medical College
  • Torikul Islam Registrar, Department of Neuromedicine, Dhaka National Medical College
  • Liton Chandra Ghosh Assistant Professor, Dept. of Nephrology, Dhaka National Medical College
  • Kanaj Kumar Barman Associate Professor, Department of Neurology, BSMMU

DOI:

https://doi.org/10.3329/jdnmch.v24i2.80056

Keywords:

CIDP, MND, EMG

Abstract

Chronic inflammatory demyelinating polyneuropathy (CIDP) is characterized by symmetrical weakness, involving both proximal and distal muscles with sensory impairment. Muscle wasting is rarely pronounced in CIDP. When a patient present with CIDP and muscle wasting may mimicking with motor neuron disease like spinomuscular atrophy (SMA), Progressive muscular atrophy (PMA). It is very important to distinguish between CIDP and motor neuron disease (MND) by clinical, laboratory and histological feature because of different effective therapeutic strategies. Our patient 35 years old male presented with tingling, numbness and weakness in all four limbs. On examination there was muscle weakness and wasting more in the distal than the proximal. Electrophysiological investigation showed mixed sensory, motor demyelinating and axonal polyradiculoneuropathy and on Electromyogram (EMG)- fibrillation was absent, CSF examination there was albuminocytological dissociation. We established this case as a CIDP though it was mimicking with MND and treatment was started with steroid and other disease modifying drugs.

J. Dhaka National Med. Coll. Hos. 2018; 24 (02): 50-53

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Published

2018-09-30

How to Cite

Khan, N. A., Wadud, S., Islam, T., Ghosh, L. C., & Barman, K. K. (2018). Chronic inflammatory demyelinating polyneuropathy maymimic with Motor neuron disease. Journal of Dhaka National Medical College & Hospital, 24(2), 50–53. https://doi.org/10.3329/jdnmch.v24i2.80056

Issue

Section

Case Reports