Toxic effects of prolonged endosulfan exposure on some blood parameters in albino rat

Authors

  • B Das Department of Genetic Engineering and Biotechnology, University of Rajshahi
  • Kawser Pervin Department of Zoology, University of Rajshahi
  • AK Roy Department of Genetic Engineering and Biotechnology, University of Rajshahi
  • Z Ferdousi Department of Genetic Engineering and Biotechnology, University of Rajshahi
  • AK Saha Department of Zoology, University of Rajshahi

DOI:

https://doi.org/10.3329/jles.v5i0.7346

Keywords:

Endosulfan, prolonged exposure, haematology, haemochemical parameters, albino rat

Abstract

Endosulfan is a worldwide used synthetic insecticide that has an important role on management of pests in agriculture. The present work was undertaken to determine the effect of endosulfan on the haematological and haemochemical parameters of albino rats. Rats were feed with 5 mg/kg body weight endosulfan in mixed food stuff for 42 days. The studies were conducted on sexually matured male rats covering five groups of animals with control. Total counts of erythrocytes and haemoglobin were decreased and leucocytes were increased in treated group. Differential counts of leucocytes showed significant increase in basophils and monocytes. The levels of serum glucose, urea, creatinine and bilirubin increased significantly, suggesting that the synthetic insecticide had remarkable toxic effects on the haematological and biochemical parameters in the experimental animals.

Key words: Endosulfan; prolonged exposure; haematology; haemochemical parameters; albino rat

DOI: 10.3329/jles.v5i0.7346

J. Life Earth Sci., Vol. 5: 29-32, 2010

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How to Cite

Das, B., Pervin, K., Roy, A., Ferdousi, Z., & Saha, A. (2011). Toxic effects of prolonged endosulfan exposure on some blood parameters in albino rat. Journal of Life and Earth Science, 5, 29–32. https://doi.org/10.3329/jles.v5i0.7346

Issue

Vol. 5 (2010)

Section

Articles

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It is a condition of publication in the Journal that author(s) assigns copyright to the Faculty of Life and Earth Sciences, University of Rajshahi, whose permission must be obtained to reproduce there from. This would ensure efficient handling of reproduction of articles for third party requests and wide dissemination at large.