Detected Atrial Arrhythmias with the 12-lead Holter System in Patients Complaining of Palpitations with Normal 12-lead ECGs - Gender and Age Differences

Authors

  • Samuel Sclarovsky Tel Aviv University, Tel Aviv
  • Kjell Christer Nikus Heart Center, Department of Cardiology, Tampere University Hospital, Tampere
  • Heini Huhtala School of Public Health, University of Tampere, Tampere
  • Markku Eskola Heart Center, Department of Cardiology, Tampere University Hospital, Tampere

DOI:

https://doi.org/10.3329/jom.v12i1.5384

Keywords:

Holter, Atrial arrhythmia, atrial fibrillation, estrogen, postmenopausal

Abstract

Objective: Hypoestrogenemia in postmenopausal female has important effects on the heart with possible arrhythmic consequences. We studied the prevalence of atrial arrhythmias in 12-lead Holter in patients with normal baseline ECGs. We used morphologic ECG data to define the origin of the arrhythmias.

Methods: Twelve lead Holter recordings in 172 consecutive patients in the community were analyzed. The prevalence of ectopic and reentry nonsustained atrial tachycardia (NSAT), atrial fibrillation, atrial flutter, and right and left premature atrial complexes, was studied in men and women. Patients aged ≥50 years and <50 years were analyzed separately.

Results: Premature atrial complexes were frequent in all the four groups. In women aged ≥50 years, the prevalence of ectopic NSAT was 57%. Women aged ≥50 years, who showed episodes of atrial fibrillation or flutter, had a prevalence of concomitant ectopic NSAT of 67 %. All the NSAT episodes were repetitive (≥10 episodes/24h). There was a striking gender difference, as the corresponding number for men in the same age group was only 17 %.

Conclusions: Ectopic NSAT is frequently associated with atrial fibrillation or flutter in women aged ≥50 years. We propose a hypothesis related to hormone metabolism and collagen expression in the heart to explain this phenomenon.

Keyword: Holter; Atrial arrhythmia; atrial fibrillation; estrogen; postmenopausal

DOI: 10.3329/jom.v12i1.5384

J Medicine 2011; 12 : 40-44

Downloads

Download data is not yet available.
Abstract
157
PDF
71

Downloads

Additional Files

Published

2011-01-21

How to Cite

Sclarovsky, S., Nikus, K. C., Huhtala, H., & Eskola, M. (2011). Detected Atrial Arrhythmias with the 12-lead Holter System in Patients Complaining of Palpitations with Normal 12-lead ECGs - Gender and Age Differences. Journal of Medicine, 12(1), 40–44. https://doi.org/10.3329/jom.v12i1.5384

Issue

Vol. 12 No. 1 (2011)

Section

Short Report

License

Authors who publish with this journal agree to the following terms:

    1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.

    1. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.

  1. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).