Low Level Laser (LED- Ga-Al- As 660) Therapy On soft Tissue Healing: A Review Update

Abstract

The normal process of soft tissue repair involves the following steps: homeostasis, inflammation ("cleaning"), demolition, proliferation, and maturing10. The homeostatic phase occurs immediately after the appearance of the lesion and depends on platelet activity and on blood coagulation process, which includes a complex release of vasoactive substances, adhesive proteins, and growth factors for the development of other stages. Later on, the inflammatory process sets in with the presence of numerous chemical mediators and inflammatory cells polymorphonuclear leukocytes, macrophages, and lymphocytes. This phase is responsible for removing necrosis tissue and combating aggressive agents installed in the wound. Next, tissue proliferation, which is responsible for "closing" the wound, sets in, with re-epithelization, fibroplasia (matrix formation), and angiogenesis, essential for the supply of oxygen and nutrients needed for healing. Finally, there is wound contraction followed by remodeling, which takes place in the collagen of the region and has the objective of increasing tensile force and diminishing the scar size. 

Journal of Science Foundation, 2015;13(2):46-51

DOI: http://dx.doi.org/10.3329/jsf.v13i2.27934