Antifungal Activity of the Essential Oils from Ocimum gratissimum L. Grown in Togo
Keywords:O.gratissimum, Antifungal, Essential oil, Thymol.
The aerial parts of Ocimum gratissimum L. (Lamiaceae) harvested in Togo was steam-distilled and investigated for essential oil composition (GC and GC/MS) and in vitro antifungal activities. Thymol (31.79 %), p-cymene (15.57 %) and Î³-terpinene (12.34 %) and were the major components of the oil. Other notable components identified in this oil were myrcene (6.94 %) and Î±-thujene (6.11 %).The in vitro antifungal activity was recorded with the minimum inhibitory concentrations (MICs) ranging from 80 to 150Â Âµl.l-1, 150 to 500 Âµl.l-1 Â and from 100 to 150 Âµl.l-1 respectively on dermatophytes, imperfect filamentous fungi and pathogenic yeasts. Likewise, on tested fungi the minimum fungicidal concentration (MFC) varied from 300 Âµl.l-1 to 500 Âµl.l-1, 500 to 700 Âµl.l-1 and from 250 to 300 Âµl.l-1, respectively on dermatophytes, imperfect filamentous fungi and pathogenic yeasts.
Keywords: O.gratissimum,Â Antifungal, Essential oil; Thymol.
Â© 2009 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights
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