Iron(III) Catalyzed Coupling of Aryl Halides: Synthesis of Terphenyl and Biphenyl Derivatives
DOI:
https://doi.org/10.3329/jsr.v5i1.12207Keywords:
Coupling, Aryl halides, Terphenyl, Biphenyl.Abstract
Iron(III) mediated coupling of arylmagnesium halides with other aryl halides produced both homo- and cross-coupled products. The reaction of phenylmagnesium bromide with 1,4-dibromobenzene as well as with 4-chlorobromobenzene in presence of FeCl3 catalyst produced both cross-coupled p-terphenyl and homo-coupled biphenyl. Under the same condition only homo-coupled 4,4¢-dipropoxybiphenyl was obtained from 4-propoxyphenylmagnesium bromide. The coupling of 4-bromophenylmagnesium bromide with bromobenzene produced both homo- and cross-coupled biaryls.
© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.
doi: http://dx.doi.org/10.3329/jsr.v5i1.12207 J. Sci. Res. 5 (1), 127-134 (2013)
Downloads
152
385
Downloads
Published
How to Cite
Issue
Section
License
© Journal of Scientific Research
Articles published in the "Journal of Scientific Research" are Open Access articles under a Creative Commons Attribution-ShareAlike 4.0 International license (CC BY-SA 4.0). This license permits use, distribution and reproduction in any medium, provided the original work is properly cited and initial publication in this journal. In addition to that, users must provide a link to the license, indicate if changes are made and distribute using the same license as original if the original content has been remixed, transformed or built upon.