Phytochemical Screening and Anti-microbial Activity Studies on <i>Leea macrophylla</i> Seed Extracts

Authors

  • M. B. Islam BCSIR Laboratories, Rajshahi
  • M. M. H. Sarkar BCSIR Laboratories, Rajshahi
  • M. Z. Shafique BCSIR Laboratories, Rajshahi
  • M. A. Jalil BCSIR Laboratories, Rajshahi
  • M. Z. Haque BCSIR, Dhaka
  • R. Amin BCSIR Laboratories, Rajshahi

DOI:

https://doi.org/10.3329/jsr.v5i2.13213

Keywords:

Leea macrophylla, Phytochemical, Screening, antimicrobial activity.

Abstract

Seed extracts of medicinal plants Leea macrophylla were investigated for phytochemical as well as antibacterial screening. Phytochemical studies of the plant extracts revealed the presence of phenolic, saponin, glycosides, carbohydrate and protein types of compounds. The antibacterial effects of the plant extracts were also tested against several human multi-drug resistant pathogens, including one gram positive and three gram negative bacterial species and one fungal species using the disc-diffusion assay. All the plant extracts showed potent anti-microbial effects against gram positive micro-organism (inhibition zone 7-19 mm) whereas none of the extracts produced any potent anti-microbial effects against gram negative bacteria. Furthermore, it has been shown that the extracts exhibit antifungal activities against candida albicans except the extract n-hexane.

Keywords: Leea macrophylla; Phytochemical screening; Anti-microbial activity.

© 2013 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.

doi: http://dx.doi.org/10.3329/jsr.v5i2.13213         J. Sci. Res. 5 (2), 399-405 (2013)

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Author Biographies

M. B. Islam, BCSIR Laboratories, Rajshahi

Drugs & Toxins Research Division

BCSIR Laboratories, Rajshahi-6206

M. M. H. Sarkar, BCSIR Laboratories, Rajshahi

Scientific Officer, Applied Botany Research Division, BCSIR Laboratories,  Rajshahi  

  

M. Z. Shafique, BCSIR Laboratories, Rajshahi

Md. Ziaullah Shafique

Principal Scientific Officer, Drugs & Toxins Research Division BCSIR Laboratories, Rajshahi  

 

M. A. Jalil, BCSIR Laboratories, Rajshahi

Md. Abdul Jalil, Senior Scientific Officer, BCSIR Laboratories, Rajshahi

 

M. Z. Haque, BCSIR, Dhaka

Dr. Md. Zahurul Haque, Chief Scientific Officer, Chemical Research Division, BCSIR, Dhaka 

R. Amin, BCSIR Laboratories, Rajshahi

Ruhul Amin

Scientific Officer, Applied Zoology Research Division

BCSIR Laboratories, Rajshahi

 

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Published

2013-04-23

How to Cite

Islam, M. B., Sarkar, M. M. H., Shafique, M. Z., Jalil, M. A., Haque, M. Z., & Amin, R. (2013). Phytochemical Screening and Anti-microbial Activity Studies on <i>Leea macrophylla</i> Seed Extracts. Journal of Scientific Research, 5(2), 399–405. https://doi.org/10.3329/jsr.v5i2.13213

Issue

Vol. 5 No. 2 (2013)

Section

Section B: Chemical and Biological Sciences

License

© Journal of Scientific Research

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Articles published in the "Journal of Scientific Research" are Open Access articles under a Creative Commons Attribution-ShareAlike 4.0 International license (CC BY-SA 4.0). This license permits use, distribution and reproduction in any medium, provided the original work is properly cited and initial publication in this journal. In addition to that, users must provide a link to the license, indicate if changes are made and distribute using the same license as original if the original content has been remixed, transformed or built upon.