Environmentally Benign Synthesis of Tetra-Substituted Imidazoles through 4-Components Strategy Mediated by (<I>S</I>)-3-Methyl-1, 1-Diphenylbutane-1, 2-Diamine
DOI:
https://doi.org/10.3329/jsr.v10i1.32794Keywords:
Multicomponent reaction, One-pot synthesis, (S)-3-methyl-1, 1-diphenylbutane-1, 2-diamine, Organocatalyst.Abstract
(S)-3-Methyl-1, 1-diphenylbutane-1, 2-diamine has been found to be a mild and effective organocatalyst for one-pot 4-components synthesis of 1, 2, 4, 5-tetra-substituted imidazoles. The key benefits of this protocol is high yielding, cost effectiveness, easy purification and above all, environmentally benign.
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