Enhanced Anticarcinogenic and Antimicrobial Response of Synthesized Tungsten Oxide Nanoparticles

Authors

  • J. kumari Research Centre, Department of Chemistry, Jyoti Nivas College Autonomous, Bangalore University, Bangalore, Karnataka, India
  • P. Mangala Research Centre, Department of Chemistry, Jyoti Nivas College Autonomous, Bangalore University, Bangalore, Karnataka, India

DOI:

https://doi.org/10.3329/jsr.v15i1.58211

Abstract

In the present study, we fabricated tungsten trioxide nanoparticles (WO3 NPs) from a tungsten complex [W(C13H10NO)3] of ligand N-salicylideneaniline with tungstic acid as the precursor. Nanoparticles were synthesized using the direct thermal decomposition method. These nanoparticles were evaluated for cytotoxicity influence on human breast cancer MCF7 cell line (adenocarcinoma). The observed results suggested that WO3 can destroy 50 % of viable cells after 24 h of incubation at 37 °C. Based on these results, we concluded that WO3 nanoparticles could be a potential drug carrier candidate against human breast cancer cells based on the amount of the drug. In addition, WO3 nanoparticles exhibited significant antimicrobial and antifungal activity.

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Published

2023-01-01

How to Cite

kumari, J., & Mangala, P. . (2023). Enhanced Anticarcinogenic and Antimicrobial Response of Synthesized Tungsten Oxide Nanoparticles. Journal of Scientific Research, 15(1), 141–157. https://doi.org/10.3329/jsr.v15i1.58211

Issue

Vol. 15 No. 1 (2023)

Section

Section B: Chemical and Biological Sciences

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.

© Journal of Scientific Research

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Articles published in the "Journal of Scientific Research" are Open Access articles under a Creative Commons Attribution-ShareAlike 4.0 International license (CC BY-SA 4.0). This license permits use, distribution and reproduction in any medium, provided the original work is properly cited and initial publication in this journal. In addition to that, users must provide a link to the license, indicate if changes are made and distribute using the same license as original if the original content has been remixed, transformed or built upon.