Biotransformation of 11-ketoprogesterone by Filamentous Fungus, <i>Fusarium lini</i>
Keywords:11-Ketoprogesterone, Steroid, Microbial transformation, Hydroxylation, Filamentous fungi, Fusarium lini.
Microbial transformation of 11-ketoprogesterone (1) by the filamentous fungi Fusarium lini was investigated. Biotransformation of 1 with F. lini resulted in the production of ten oxidative metabolites (2-11). Structures of these metabolites were deduced by spectroscopic analysis and seven of them, 5-11, were found to be new metabolites.
Keywords: 11-Ketoprogesterone; Steroid; Microbial transformation; Hydroxylation; Filamentous fungi; Fusarium lini.
© 2011 JSR Publications. ISSN: 2070-0237 (Print); 2070-0245 (Online). All rights reserved.
doi:10.3329/jsr.v2i2.6221 J. Sci. Res. 3 (2), 347-356 (2011)
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