Prevalence of Helicobacter Pylori Infection among Patients of Functional Dyspepsia in A Tertiary Level Hospital in Bangladesh

Abstract

The prevalence of Helicobacter pylori infection in Asian population is higher than that of the Western population. A cross-sectional, observational study was conducted in the Department of Gastroenterology, Sher-E-Bangla Medical College Hospital, Barishal, Bangladesh, between September 2021 and March 2022, to determine frequency of Helicobacter pylori infection among patients suffering from functional dyspepsia. A total of 100 patients of functional dyspepsia were selected based on inclusion and exclusion criteria for this study. Patients having functional dyspepsia were included as per Rome IV criteria. Patients were excluded if any of the following is observed: overlapping symptoms e.g., predominant reflux and IBS, significant comorbidities, severe psychiatric disease, pregnancy, previous gastric surgery, having contraindication to undergo endoscopic procedure, alcohol and other substance abusers, patients taking anti-ulcerant and triple therapy within the last one and half month. Endoscopic examination of the upper gastrointestinal tract and Campylobacter-like organism (CLO) tests were done. Descriptive statistics was used for the interpretation of the findings. In our study patients, male-female ratio of 1.08:1.0. The mean age of the patients was 35.37±10.13 years, while the mean age of the H. pylori positive population was 33.76±09.04 years. Postprandial burning was the most common symptom found in 78% of cases. Based on CLO test, H. pylori infection was found in 39% cases of functional dyspepsia patients. Male (42.3%) and female (35.4%) were almost equally affected (p>0.05). 43.6% of CLO test positive patients were in the 26–35 years age-group, followed by 36–45 years age-group (28.2%), 18–25 years age-group (17.9%), and >45 years age-group (10.3%), i.e., young and middle aged patients were found more infected (p<0.05).

Mugda Med Coll J. 2025; 8(2): 78-83