Identification of hepatitis a virus antibody among Bangladeshi children and their correlation with socioeconomic condition

Authors

  • Salahuddin Mahmud Assistant Professor, Dhaka Shishu Hospital, Dhaka
  • ASM Bazlul Karim Paediatric Gastroenterology & Nutrition, BSMMU, Dhaka
  • Jahangir Alam Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • SK Saha Dept. of Microbiology, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • Syed Shafi Ahmed Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • MM Ziaul Islam Assistant Professor, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • NK Sarker Assistant Professor, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • AS Munshi Assistant Professor, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • Shaoli Sarker Assistant Professor, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka
  • Mahenaz Afroz Assistant Professor of Gynae, NICRH, Dhaka
  • Farhana Tasneem Assistant Professor, Bangladesh Institute of Child Health, Dhaka Shishu Hospital, Dhaka

DOI:

https://doi.org/10.3329/nimcj.v6i1.23152

Keywords:

Anti-hepatitis A virus (HAV), HAV seroprevalence

Abstract

Background : Hepatitis A virus infection is endemic in many developing countries including Bangladesh. Children infected with Hepatitis-A virus typically have asymptomatic disease.

Objective : To observe the anti-HAV positivity in children & to determine any relation between anti-HAV positivity & socioeconomic condition.

Materials & Methods : A cross sectional observational study was conducted at Bangabandhu Sheikh Mujib Medical University (BSMMU) Hospital & Dhaka Shishu (Children) Hospital (DSH) from July 2008 to June 2009. Serum samples from 254 children aged between 1-15 years were tested for antibody (IgM & IgG) against hepatitis A virus (HAV) and detailed history was taken to find out the associated risk factors like residence, family income, source of drinking water, sanitation facility etc.

Results : Hepatitis A virus antibody was positive in 141 (55.5%) of 254 children. Among all children anti-HAV positivity was significantly higher (p=0.004) in lower income group (64.8%) than higher income group (47.0%). Anti-HAV positivity was significantly higher (93.8%) in non-sanitary latrine users & in those who used unsafe drinking water.(p=0.006)

Conclusions : Majority of children were found sero-positive against HAV by 15 year of age. Anti-HAV positivity was significantly higher in lower socioeconomic group.

Northern International Medical College Journal Vol.6(1) 2014: 12-14

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Author Biography

Salahuddin Mahmud, Assistant Professor, Dhaka Shishu Hospital, Dhaka



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Published

2015-05-01

How to Cite

Mahmud, S., Karim, A. B., Alam, J., Saha, S., Ahmed, S. S., Islam, M. Z., Sarker, N., Munshi, A., Sarker, S., Afroz, M., & Tasneem, F. (2015). Identification of hepatitis a virus antibody among Bangladeshi children and their correlation with socioeconomic condition. Northern International Medical College Journal, 6(1), 12–14. https://doi.org/10.3329/nimcj.v6i1.23152

Issue

Vol. 6 No. 1 (2014)

Section

Original Articles